ArticlePloS one2014
Metabolomic analysis of three Mollicute species.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Real-time monitoring of metabolic plasticity in Mycoplasma gallisepticum under varying nutrient conditions via DART-HRMS.Scientific reports · 2026Article
- When less is more: cell size reduction as a metabolic lifeline inFrontiers in microbiology · 2026Article
- Plasma metabolomics of Mycoplasma synoviae infection in SPF White Leghorn hens by liquid chromatography-tandem mass spectrometry.Veterinary research · 2025Article
- A sweeping view of avian mycoplasmas biology drawn from comparative genomic analyses.BMC genomics · 2025Article
- Enhancing cellulose acetate biodegradability in cigarette filters: an in-depth analysis of thermal alkaline pretreatment, microbial dynamics, and breakdown pathway prediction.Microbial cell factories · 2024Article
- Taxonomic and environmental distribution of bacterial amino acid auxotrophies.Nature communications · 2023Article
- UHPLC/MS-Based Untargeted Metabolomics Reveals Metabolic Characteristics of Clinical Strain ofMicroorganisms · 2023Article
- Flow-Cytometric Method for Viability Analysis of Mycoplasma gallisepticum and Other Cell-Culture-Contaminant Mollicutes.Current microbiology · 2021Article
- A Review ofFrontiers in veterinary science · 2021Review
- Structure-based inhibitors targeting the alpha-helical domain of the Spiroplasma melliferum histone-like HU protein.Scientific reports · 2020Article
- Comparison of Five Extraction Methods for Intracellular Metabolites of Salmonella typhimurium.Current microbiology · 2019Article
- Essential metabolism for a minimal cell.eLife · 2019Article
- Response induced in Mycoplasma gallisepticum under heat shock might be relevant to infection process.Scientific reports · 2017Article
- Outer membrane vesicles secreted by pathogenic and nonpathogenic Bacteroides fragilis represent different metabolic activities.Scientific reports · 2017Article
- Phase Transition of the Bacterium upon Invasion of a Host Cell as a Mechanism of Adaptation: a Mycoplasma gallisepticum Model.Scientific reports · 2016Article
- Reconstruction of Transcription Control Networks in Mollicutes by High-Throughput Identification of Promoters.Frontiers in microbiology · 2016Article
- Draft Genome Sequence of "Candidatus Hepatoplasma crinochetorum" Ps, a Bacterial Symbiont in the Hepatopancreas of the Terrestrial Isopod Porcellio scaber.Genome announcements · 2015Article
- Survival of free-living Acholeplasma in aerated pig manure slurry revealed by (13)C-labeled bacterial biomass probing.Frontiers in microbiology · 2015Article
- Comparative Metabolomics ofmSystemsArticle
- Mycoplasmas and Their Antibiotic Resistance: The Problems and Prospects in Controlling Infections.Acta naturaeArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a systematic study of three bacterial species that belong to the class Mollicutes, the smallest and simplest bacteria, Spiroplasma melliferum, Mycoplasma gallisepticum, and Acholeplasma laidlawii. To understand the difference in the basic principles of metabolism regulation and adaptation to environmental conditions in the three species, we analyzed the metabolome of these bacteria. Metabolic pathways were reconstructed using the proteogenomic annotation data provided by our lab. The results of metabolome, proteome and genome profiling suggest a fundamental difference in the adaptation of the three closely related Mollicute species to stress conditions. As the transaldolase is not annotated in Mollicutes, we propose variants of the pentose phosphate pathway catalyzed by annotated enzymes for three species. For metabolite detection we employed high performance liquid chromatography coupled with mass spectrometry. We used liquid chromatography method - hydrophilic interaction chromatography with silica column - as it effectively separates highly polar cellular metabolites prior to their detection by mass spectrometer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.