Evidence map›Paper›PMID 24594903›Full record

Trial reportAddictive behaviors2014

Smoking- and menstrual-related symptomatology during short-term smoking abstinence by menstrual phase and depressive symptoms.

Sharon S Allen, Alicia M Allen, Nicole Tosun, Scott Lunos, Mustafa al'Absi, Dorothy Hatsukami

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic and meta-analytic review of research examining the impact of menstrual cycle phase and ovarian hormones on smoking and cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Pooled it
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  18. Reply to Dr Howe.Journal of addiction medicine
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sharon S AllenDepartment of Family Medicine & Community Health Medical School, University of Minnesota, 420 Delaware Street SE, Room A682, Minneapolis, MN 55455, United States.
Alicia M AllenDepartment of Family Medicine & Community Health, Medical School, University of Minnesota, 717 Delaware Street SE, Room 422, Minneapolis, MN 55414, United States.
Nicole TosunDepartment of Family Medicine & Community Health, Medical School, University of Minnesota, 717 Delaware Street SE, Room 261, Minneapolis, MN 55414, United States.
Scott LunosBiostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, 717 Delaware Street SE, Suite 132, Minneapolis, MN 55414, United States.
Mustafa al'AbsiDepartment of Behavioral Sciences, Medical School, University of Minnesota, Duluth 1035 University Drive, 236 SMed, D601A, Duluth, MN 55812, United States.
Dorothy HatsukamiDepartment of Psychiatry, Medical School, University of Minnesota, 717 Delaware Street SE, Room 256, Minneapolis, MN 55414, United States.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
YOUTH DRUG ABUSE, ADHD, AND RELATED DISRUPTIVE DISORDERSM01RR000400 · NCRR · UNIVERSITY OF MINNESOTA TWIN CITIES · PI KOTLYAR, MICHAEL · 1985 to 2009
$33.7M
TOBACCO CESSATION IN POSTMENOPAUSAL WOMENR01DA008075 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ALLEN, SHARON S · 1993 to 2016
$5.5M
NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1TR000114NCRR NIH HHS M01 RR000400NIDA NIH HHS R01 DA008075NIDA NIH HHS R01DA08075
6 · The paper itself

Abstract

Menstrual phase and depressive symptoms are known to minimize quit attempts in women. Therefore, the influence of these factors on smoking- and menstrual-related symptomatology during acute smoking cessation was investigated in a controlled cross-over lab-study. Participants (n=147) completed two six-day testing weeks during their menstrual cycle with testing order randomly assigned (follicular vs. luteal). The testing week consisted of two days of ad libitum smoking followed by four days of biochemically verified smoking abstinence. Daily symptomatology measures were collected. Out of the 11 total symptoms investigated, six were significantly associated with menstrual phase and nine were significantly associated with level of depressive symptoms. Two significant interactions were noted indicating that there may be a stronger association between depressive symptoms with negative affect and premenstrual pain during the follicular phase compared to the luteal phase. Overall, these observations suggest that during acute smoking abstinence in premenopausal smokers, there is an association between depressive symptoms and symptomatology whereas menstrual phase appears to have less of an effect. Further study is needed to determine the effect of these observations on smoking cessation outcomes, as well as to define the mechanism of menstrual phase and depressive symptoms on smoking-related symptomatology.

Indexed as

AdolescentAdultCross-Over StudiesDepressionFemaleFollicular PhaseHumansLuteal PhaseMenstrual CycleMenstruation DisturbancesSmokingSmoking CessationSubstance Withdrawal SyndromeYoung AdultDepressive symptomsMenstrual cycleSmoking cessationWithdrawal

Identifiers

PMID24594903
PMCPMC4010248

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.