Evidence map›Paper›PMID 24594837›Full record

ArticleHealth & place2014

Stepping towards causation in studies of neighborhood and environmental effects: how twin research can overcome problems of selection and reverse causation.

Glen E Duncan, Brianna Mills, Eric Strachan, Philip Hurvitz, Ruizhu Huang, Anne Vernez Moudon, Eric Turkheimer

Abstract read
In one paragraph

Article in Health & place, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neighborhood Tax Foreclosures, Educational Attainment, and Preterm Birth among Urban African American Women.International journal of environmental research and public health · 2019
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cross Sectional Association between Spatially Measured Walking Bouts and Neighborhood Walkability.International journal of environmental research and public health · 2016
    Article
  17. Article
  18. Access to green space, physical activity and mental health: a twin study.Journal of epidemiology and community health · 2015
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Glen E DuncanDepartment of Epidemiology, University of Washington, Seattle, WA 98195, USA; Interdisciplinary Graduate Program in Nutritional Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address: duncag@u.washington.edu.
Brianna MillsDepartment of Epidemiology, University of Washington, Seattle, WA 98195, USA.
Eric StrachanDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA.
Philip HurvitzDepartment of Urban Design and Planning, Urban Form Lab, University of Washington, Seattle, WA 98195, USA.
Ruizhu HuangInterdisciplinary PhD Program in Urban Design and Planning, Urban Form Lab, University of Washington, Seattle, WA 98195, USA.
Anne Vernez MoudonDepartment of Epidemiology, University of Washington, Seattle, WA 98195, USA; Department of Urban Design and Planning, Urban Form Lab, University of Washington, Seattle, WA 98195, USA.
Eric TurkheimerDepartment of Psychology, University of Virginia, Charlottesville, VA 22904, USA.

Funding

Building a Unique National Community Based Twin RepositoryRC2HL103416 · NHLBI · UNIVERSITY OF WASHINGTON · PI BUCHWALD, DEDRA S · 2009 to 2010
$7.7M
TWINStudy of Environment, Lifestyle Behaviors, and HealthR01AG042176 · NIA · WASHINGTON STATE UNIVERSITY · PI DUNCAN, GLEN E · 2011 to 2014
$2.2M
NHLBI NIH HHS RC2 HL103416NHLBI NIH HHS RC2HL103416NIA NIH HHS R01 AG042176NIA NIH HHS R01AG042176
6 · The paper itself

Abstract

No causal evidence is available to translate associations between neighborhood characteristics and health outcomes into beneficial changes to built environments. Observed associations may be causal or result from uncontrolled confounds related to family upbringing. Twin designs can help neighborhood effects studies overcome selection and reverse causation problems in specifying causal mechanisms. Beyond quantifying genetic effects (i.e., heritability coefficients), we provide examples of innovative measures and analytic methods that use twins as quasi-experimental controls for confounding by environmental effects. We conclude that collaboration among investigators from multiple fields can move the field forward by designing studies that step toward causation.

Indexed as

Twin Studies as TopicCausalityEnvironment DesignHumansModels, TheoreticalPatient SelectionResidence CharacteristicsRisk Reduction BehaviorCausalityEnvironment designLifestyle risk reductionSocial and built environmentsTwin studies

Identifiers

PMID24594837
PMCPMC4004691

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.