ReviewNeuroscience and biobehavioral reviews2014
Moving forward: age effects on the cerebellum underlie cognitive and motor declines.
Review in Neuroscience and biobehavioral reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
114 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Verbal fluency dual-tasks show greater age-related cognitive-motor interference: a meta-analysis of walking performance.Experimental brain research · 2025Pooled it
- Differential vulnerability of the cerebellum in healthy ageing and Alzheimer's disease.NeuroImage. Clinical · 2021Pooled it
- Shaky scaffolding: Age differences in cerebellar activation revealed through activation likelihood estimation meta-analysis.Human brain mapping · 2020Pooled it
- Effects of HD-tDCS targeting prefrontal cortex, cerebellum, and motor cortex on dual-task gait in older adults.Scientific reports · 2025Trial
- Comparing the effects of cerebellar and prefrontal anodal transcranial direct current stimulation concurrent with postural training on balance and fatigue in patients with multiple sclerosis: a double-blind, randomized, sham-controlled trial.Experimental brain research · 2024Trial
- Glucose administration and cognitive function: differential effects of age and effort during a dual task paradigm in younger and older adults.Psychopharmacology · 2015Trial
- Combined cognitive-psychological-physical intervention induces reorganization of intrinsic functional brain architecture in older adults.Neural plasticity · 2015Trial
- Adults up to 80 years old maintain effective movement planning when facing complex body dynamics.GeroScience · 2026Article
- Article
- A reproducible low-dimensional architecture of human white-matter connectivity.Research square · 2026Article
- Cerebellar aging is spatially heterogeneous and supports cognitive resilience in later life.Nature neuroscience · 2026Article
- Protracted prediction: Neurodevelopment of reward processing in the adolescent cerebellum.bioRxiv : the preprint server for biology · 2026Article
- Speech as a dynamic biomarker of physical aging: a longitudinal study.GeroScience · 2026Article
- Temporal Probability-Guided Shifts in Temporal Preparation Away from the Beat Under a Distracting Rhythm in Aging.Behavioral sciences (Basel, Switzerland) · 2026Article
- Functional connectivity patterns of the cerebellar components of intrinsic connectivity networks in clinically diagnosed probable Alzheimer's disease.BMC medical imaging · 2026Article
- Combining Cognitive and Sensorimotor Assessments to Facilitate Detection of Age-Related Cognitive Decline.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Age-group differences in diffusion MRI characteristics of cortico-cerebellar tracts and their association with bimanual performance.Frontiers in aging neuroscience · 2026Article
- Protocol for an unblinded randomised controlled feasibility trial of Piano Instruction for Adult Novices as Online Cognitive intervention (PIANO-Cog): a novel remote piano training programme for cognitive and motor functions in older age.Pilot and feasibility studies · 2025Article
- Article
- Mapping hippocampal-cerebellar functional connectivity across the human adult lifespan.Communications biology · 2025Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Though the cortical contributions to age-related declines in motor and cognitive performance are well-known, the potential contributions of the cerebellum are less clear. The diverse functions of the cerebellum make it an important structure to investigate in aging. Here, we review the extant literature on this topic. To date, there is evidence to indicate that there are morphological age differences in the cerebellum that are linked to motor and cognitive behavior. Cerebellar morphology is often as good as - or even better - at predicting performance than the prefrontal cortex. We also touch on the few studies using functional neuroimaging and connectivity analyses that further implicate the cerebellum in age-related performance declines. Importantly, we provide a conceptual framework for the cerebellum influencing age differences in performance, centered on the notion of degraded internal models. The evidence indicating that cerebellar age differences associate with performance highlights the need for additional work in this domain to further elucidate the role of the cerebellum in age differences in movement control and cognitive function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.