Evidence map›Paper›PMID 24592315›Full record

ReviewF1000prime reports2014

A CRISPR method for genome engineering.

Royce Wilkinson, Blake Wiedenheft

Abstract readReview
In one paragraph

Review in F1000prime reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. CRISPR-Cpf1 system and its applications in animal genome editing.Molecular genetics and genomics : MGG · 2024
    Review
  2. Portable CRISPR-Cas9Applied and environmental microbiology · 2021
    Article
  3. Can Designer Indels Be Tailored by Gene Editing?: Can Indels Be Customized?BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Article
  4. Article
  5. Biotechnology reports (Amsterdam, Netherlands) · 2018
    Article
  6. Oral Administration of RecombinantFrontiers in microbiology · 2018
    Article
  7. Article
  8. Article
  9. Salient Features of Endonuclease Platforms for Therapeutic Genome Editing.Molecular therapy : the journal of the American Society of Gene Therapy · 2016
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. A CRISPR view of development.Genes & development · 2014
    Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Royce WilkinsonDepartment of Immunology and Infectious Diseases, Montana State University Bozeman, MT 59717 USA.
Blake WiedenheftDepartment of Immunology and Infectious Diseases, Montana State University Bozeman, MT 59717 USA.

Funding

Center for Zoonotic and Emerging Infectious DiseasesP20GM103500 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T · 2012 to 2013
$4.2M
Structure, Function and Application of CRISPR RNA-guided Immunity in BacteriaR01GM108888 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI WIEDENHEFT, BLAKE A · 2014 to 2019
$1.6M
NIGMS NIH HHS P20 GM103500NIGMS NIH HHS R01 GM108888
6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided adaptive immune systems that protect bacteria and archaea from infection by viruses are now being routinely repurposed for genome engineering in a wide variety of cell types and multicellular organisms.

Identifiers

PMID24592315
PMCPMC3883426

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.