ReviewFrontiers in pharmacology2014
Female reproductive tract pain: targets, challenges, and outcomes.
Review in Frontiers in pharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Management of anxiety and pain perception in women undergoing office hysteroscopy: a systematic review.Archives of gynecology and obstetrics · 2020Pooled it
- Article
- Application of Mesenchymal Stem Cells in Female Infertility Treatment: Protocols and Preliminary Results.Life (Basel, Switzerland) · 2024Review
- Localizing somatic symptoms associated with childhood maltreatment.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Therapeutic potential and mechanisms of sacral nerve stimulation for gastrointestinal diseases.Journal of translational internal medicine · 2023Article
- LncRNA NEAT1 affects endometrial receptivity by regulating HOXA10 promoter activity.Cell cycle (Georgetown, Tex.) · 2022Article
- Mesenchymal stem cells to treat female infertility; future perspective and challenges: A review.International journal of reproductive biomedicine · 2022Review
- Review
- A Role for Bradykinin Signaling in Chronic Vulvar Pain.The journal of pain · 2016Article
- Identification of novel mechanisms involved in generating localized vulvodynia pain.American journal of obstetrics and gynecology · 2015Article
- Neurobiological mechanisms of pelvic pain.BioMed research international · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain from the female reproductive tract (FRT) is a significant clinical problem for which there are few effective therapies. The complex neuroanatomy of pelvic organs not only makes diagnosis of pelvic pain disorders difficult but represents a challenge to development of targeted therapies. A number of potential therapeutic targets have been identified on sensory neurons supplying the FRT but our knowledge on the basic neurophysiology of these neurons is limited compared with other viscera. Until this is addressed we can only guess if the new experimental therapies proposed for somatic, gastrointestinal, or bladder pain will translate to the FRT. Once suitable therapeutic targets become clear, the next challenge is drug delivery. The FRT represents a promising system for topical drug delivery that could be tailored to act locally or systemically depending on formulation. Development of these therapies and their delivery systems will need to be done in concert with more robust in vivo and in vitro models of FRT pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.