Evidence map›Paper›PMID 24592112›Full record

ReviewJournal of the Turkish German Gynecological Association2013

A close look at the contraction and relaxation of the myometrium; the role of calcium.

Bilge Pehlivanoğlu, Sibel Bayrak, Murat Doğan

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Journal of the Turkish German Gynecological Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07056062 (Effect of Oral Calcium Carbonate on Uterine Contractility and Labor Outcomes), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07056062 phase2 / phase3completednot on this mapstarted 2024, after this paper: background citation

Effect of Oral Calcium Carbonate on Uterine Contractility and Labor Outcomes: A Randomized Controlled Trial

TypeinterventionalSponsorArrowhead Regional Medical CenterRan2024 to 2025Enrolled89ConditionsUterine Contraction, Labor Complication, Labor Active Dilated Cm, Labor DystociaArmsCalcium carbonate
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Functions of RhoA in the female reproductive system.Reproductive and developmental medicine · 2025
    Review
  7. Article
  8. A bioprinted model of pregnant human uterine myometrium.Frontiers in bioengineering and biotechnology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  17. Anti-inflammatory and utero-relaxant effect of α-bisabolol on the pregnant human uterus.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2018
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bilge PehlivanoğluDepartment of Physiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Sibel BayrakDepartment of Physiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Murat DoğanDepartment of Physiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function and regulation of the myometrium, especially during pregnancy, labour and birth are important in reproductive physiology. It is crucial to understand the mechanisms that generate and modulate uterine contractility in order to be able to prevent and/or treat the problems related with the myometrium. A limited understanding of the cellular and molecular events underlying these phenomena complicates the situation. Various agonists, hormones, transmitters and/or chemicals are related to the regulation of the functions of the myometrium. Although notable advances regarding the key steps in receptor signalling explaining the actions of these factors have been achieved, a good deal of information is still necessary to understand this vital process. A better comprehension of myometrium physiology and the translation of research findings to clinical settings will help progress in women's health. In this review, we attempt to present a critical overview of myometrial functions and focus specifically on the role of calcium.

Indexed as

calciumcontractionMyocytesrelaxationsensitisation

Identifiers

PMID24592112
PMCPMC3935537
OpenAlexW2024631449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.