Evidence map›Paper›PMID 24591832›Full record

ReviewNeuropsychiatric disease and treatment2014

What's in the pipeline? Drugs in development for autism spectrum disorder.

Min Sung, Chee Hon Chin, Choon Guan Lim, Hwee Sen Alvin Liew, Chau Sian Lim, Espérance Kashala, Shih-Jen Weng

Open access · goldAbstract readReview
In one paragraph

Review in Neuropsychiatric disease and treatment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Practitioner's review: medication for children and adolescents with autism spectrum disorder (ASD) and comorbid conditions.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2021
    Review
  3. Review
  4. Frontiers in genetics · 2019
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Min SungDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Chee Hon ChinDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Choon Guan LimDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Hwee Sen Alvin LiewDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Chau Sian LimDepartment of Psychological Medicine, Khoo Teck Puat Hospital, Singapore.
Espérance KashalaDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Shih-Jen WengDepartment of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore.
Institute of Mental Health · SGKhoo Teck Puat Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities) that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed.

Indexed as

Asperger’s syndromeautismmedicationpharmacologytreatment

Identifiers

PMID24591832
PMCPMC3934669
OpenAlexW2015178430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.