ArticleEthiopian journal of health sciences2014
Evaluation of clinical and pathological response after two cycles of neoadjuvant chemotherapy on Sudanese patients with locally advanced breast cancer.
Article in Ethiopian journal of health sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Neoadjuvant chemotherapy in women with triple-negative breast cancer: real world results from Western Kenya.The oncologist · 2026Article
- Article
- Locally advanced breast cancer treated with neoadjuvant chemotherapy: Is breast-conserving surgery feasible?Annals of medicine and surgery (2012) · 2021Article
- A Study on Clinical and Pathological Responses to Neoadjuvant Chemotherapy in Breast Carcinoma.Breast cancer (Dove Medical Press) · 2020Article
- An update on the management of breast cancer in Africa.Infectious agents and cancer · 2017Review
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Abstract
backgroundThe use of neoadjuvant chemotherapy in treating breast cancer has shown efficacy in downstaging primary tumors, and allows breast conservative surgery to be performed instead of mastectomy. This study aims to evaluate patterns of clinical and pathological response after two cycles of neoadjuvant chemotherapy in patients with locally advanced breast cancer. MATERIALS AND
methodsThis is a prospective study. Ninety-eight patients who presented from April 2009 through May 2011 with locally advanced breast cancer and treated with neoadjuvant chemotherapy were included.
resultsThe clinical response rate was 83%; 11 patients (11.2%) had a complete clinical remission (cCR); 71 had a partial remission (72.4%); 13 had stable disease (13.3%), and 3 had progressive disease (3.1%). Seven patients had complete pathological response.
conclusionNeoadjuvant chemotherapy can achieve a high objective response rate in patients with locally advanced breast cancer even after two cycles. We recommend further research to find predictors for response.
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