ArticleDisease markers2014
New markers: urine xanthine oxidase and myeloperoxidase in the early detection of urinary tract infection.
Article in Disease markers, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 43 citations in OpenAlex.
- Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial.BMJ (Clinical research ed.) · 2017Trial
- Presence of neutrophil extracellular traps (NETs) in different types of human urinary tract infections (UTI). A pilot study.Frontiers in immunology · 2026Article
- Biomarkers innovation in urinary tract infections: Insights into pathophysiology, antibiotic resistance, and clinical applications.World journal of nephrology · 2025Review
- Towards individualised treatment of urinary tract infections.Communications medicine · 2025Article
- Urinary Tract Infections Detection with Molecular Biomarkers.Biomolecules · 2024Review
- A cynomolgus monkeyInfection and immunity · 2024Article
- Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study.Frontiers in physiology · 2024Article
- Urinary Biomarkers and Point-of-Care Urinalysis Devices for Early Diagnosis and Management of Disease: A Review.Biomedicines · 2023Review
- Neutrophil extracellular traps in urinary tract infection.Frontiers in pediatrics · 2023Article
- Evaluation of myeloperoxidase in synovial fluid as a biomarker for chronic periprosthetic joint infection.International orthopaedics · 2020Article
- Levonadifloxacin, a Novel Benzoquinolizine Fluoroquinolone, Modulates Lipopolysaccharide-Induced Inflammatory Responses in Human Whole-Blood Assay and Murine Acute Lung Injury Model.Antimicrobial agents and chemotherapy · 2020Article
- Experimentally Induced Bladder Permeability Evokes Bladder Afferent Hypersensitivity in the Absence of Inflammation.Frontiers in neuroscience · 2020Article
- Article
- Correlations between related-purine derivatives and renal disorders in patients with psoriasis vulgaris.Experimental and therapeutic medicine · 2019Article
- Article
- Salivary Myeloperoxidase, Assessed by 3,3'-Diaminobenzidine Colorimetry, Can Differentiate Periodontal Patients from Nonperiodontal Subjects.Enzyme research · 2016Article
- Advancing Urinary Protein Biomarker Discovery by Data-Independent Acquisition on a Quadrupole-Orbitrap Mass Spectrometer.Journal of proteome research · 2015Article
- A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma.Nature communications · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to evaluate if xanthine oxidase and myeloperoxidase levels quantitation method may alternate routine culture method, which takes more time in the diagnosis of urinary tract infections. MATERIAL AND
methodsFive hundred and forty-nine outpatients who had admitted to Clinic Microbiology Laboratory were included in the study. The microorganisms were identified by using VITEK System. The urine specimens that were negative from the quantitative urine culture were used as controls. The activities of MPO and XO in spot urine were measured by spectrophotometric method.
resultsThrough the urine cultures, 167 bacteria were isolated from 163 urine specimens; 386 cultures yielded no bacterial growth. E. coli was the most frequent pathogen. In infection with E. coli both XO and MPO levels were increased the most. The sensitivity, specificity, positive predictive value, and negative predictive value for XO were 100%, 100%, 100%, and 100%, respectively. These values for MPO were 87%, 100%, 100%, and 94%, respectively.
conclusionThese data obtained suggest that urine XO and MPO levels may be new markers in the early detection of UTI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.