SynthesisEuropean heart journal2014
Outbursts of anger as a trigger of acute cardiovascular events: a systematic review and meta-analysis.
Synthesis in European heart journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cognitive behavioral therapy for the management of cardiometabolic disease risk factors; a systematic meta-review of meta-analyses.BMC psychiatry · 2025Pooled it
- The impact of gratitude interventions on patients with cardiovascular disease: a systematic review.Frontiers in psychology · 2023Pooled it
- Guideline
- Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study.Journal of the American Heart Association · 2024Trial
- The Effects of Heart Rate Variability (HRV) Biofeedback on HRV Reactivity and Recovery During and After Anger Recall Task for Patients with Coronary Artery Disease.Applied psychophysiology and biofeedback · 2022Trial
- Putative mechanisms Underlying Myocardial infarction onset and Emotions (PUME): a randomised controlled study protocol.BMJ open · 2018Trial
- Applying a causal biopsychosocial model to guide medicine and psychiatry fifty years after Engel.Communications medicine · 2026Review
- Habitual Aerobic Exercise Is Associated with Reduced Negative Emotional Elicitation: An fNIRS Study.Brain sciences · 2026Article
- Stress and Acute Coronary Syndrome.Cardiology research · 2025Review
- Integrating Emotional Stress and Lipid Lowering in Cardiovascular Disease Management: The Future of Precision Cardiovascular Prevention.Journal of clinical medicine · 2025Article
- Trait anger is related to the ability to recognize facial emotions-but only in men.Frontiers in psychology · 2025Article
- It is not just a game. Do soccer matches affect cardiovascular events?Archives of medical science : AMS · 2025Article
- Stress and cardiovascular disease: an update.Nature reviews. Cardiology · 2024Review
- Slow Well-Being Gardening: Creating a Sensor Network for Radiation Therapy Patients via Horticultural Therapeutic Activity.Sensors (Basel, Switzerland) · 2024Article
- Female adolescents' early life stress and body mass index: Differential effects of anger and anxiety in response to rejection.Journal of adolescence · 2024Article
- Psychological Health and Ischemic Heart Disease in Women: A Review of Current Evidence and Clinical Considerations across the Healthspan.Current atherosclerosis reports · 2024Review
- Negative Emotions Are Associated With Older Self-perceived Age: A Cross-section Study From the UK Biobank.International journal of health policy and management · 2024Article
- Coronary microvascular function in male physicians with burnout and job stress: an observational study.BMC medicine · 2023Observational
- A retrospective review of out of hospital cardiac arrest at Gillette Stadium: 10 years of experience at a large sports venue.Resuscitation plus · 2023Article
- Risk of myocardial infarction after invasive outpatient procedures.Heart (British Cardiac Society) · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
aimShort-term psychological stress is associated with an immediate physiological response and may be associated with a transiently higher risk of cardiovascular events. The aim of this study was to determine whether brief episodes of anger trigger the onset of acute myocardial infarction (MI), acute coronary syndromes (ACS), ischaemic and haemorrhagic stroke, and ventricular arrhythmia. METHODS AND
resultsWe performed a systematic review of studies evaluating whether outbursts of anger are associated with the short-term risk of heart attacks, strokes, and disturbances in cardiac rhythm that occur in everyday life. We performed a literature search of the CINAHL, Embase, PubMed, and PsycINFO databases from January 1966 to June 2013 and reviewed the reference lists of retrieved articles and included meeting abstracts and unpublished results from experts in the field. Incidence rate ratios and 95% confidence intervals were calculated with inverse-variance-weighted random-effect models. The systematic review included nine independent case-crossover studies of anger outbursts and MI/ACS (four studies), ischaemic stroke (two studies), ruptured intracranial aneurysm (one study), and ventricular arrhythmia (two studies). There was evidence of substantial heterogeneity between the studies (I(2) = 92.5% for MI/ACS and 89.8% for ischaemic stroke). Despite the heterogeneity, all studies found that, compared with other times, there was a higher rate of cardiovascular events in the 2h following outbursts of anger.
conclusionThere is a higher risk of cardiovascular events shortly after outbursts of anger.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.