ReviewCold Spring Harbor perspectives in medicine2014
Adipocytes in skin health and disease.
Review in Cold Spring Harbor perspectives in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 105 citations in OpenAlex.
- TFC-1326 Compound Reduces Clinical Signs of Skin Aging. Evidence From In Vitro Human Adipose and Skin Models and Pilot Clinical Trial.Journal of cosmetic dermatology · 2025Trial
- Biomimetic Dermal Substitutes for Skin Reconstruction: Advances in Scaffold Design, Biological Integration, and Clinical Performance.Journal of functional biomaterials · 2026Review
- A Vascularized, Adipose-Containing Human Skin Equivalent Enables Long-Term Culture and Models Orthopoxvirus-Mediated Immune Suppression.Journal of functional biomaterials · 2026Article
- Morphostructural Analysis of PAH-Rich Human Adipose Tissue: A Potential Silent Sequestration Site.International journal of molecular sciences · 2026Article
- Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect.Journal of radiation research · 2025Review
- The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease.Biomolecules · 2025Review
- Atgl-Dependent Adipocyte Lipolysis Promotes Lipodystrophy and Restrains Fibrogenic Responses during Skin Fibrosis.The Journal of investigative dermatology · 2025Article
- Stromal lipid species dictate melanoma metastasis and tropism.Cancer cell · 2025Article
- A bioactive three-layered skin substitute based on ECM components effectively promotes skin wound healing and regeneration.Materials today. Bio · 2025Article
- The role of lipids in promoting hair growth through HIF-1 signaling pathway.Scientific reports · 2025Article
- Anatomy, Histology, and Embryonic Origin of Adipose Tissue: Insights to Understand Adipose Tissue Homofunctionality in Regeneration and Therapies.Advances in experimental medicine and biology · 2025Review
- Extracellular Vesicles Derived from Adipose Stem Cells Alleviate Systemic Sclerosis by Inhibiting TGF-β Pathway.Biomolecules & therapeutics · 2024Article
- Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism.Tissue engineering and regenerative medicine · 2024Article
- Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation during full-thickness craniomaxillofacial skin reconstruction.Bioactive materials · 2024Article
- Low-temperature pulverization-specificAnimal cells and systems · 2024Article
- Regulated adipose tissue-specific expression of humaniScience · 2023Article
- Obesity and the risk of cardiometabolic diseases.Nature reviews. Cardiology · 2023Review
- The Sympathetic Innervation of Adipose Tissues: Regulation, Functions, and Plasticity.Comprehensive Physiology · 2023Article
- A novel combined technology for treating hypertrophic scars: adipose tissue extract combined with fractional COFrontiers in physiology · 2023Article
- Zinc and Zinc Transporters in Dermatology.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Adipocytes are intimately associated with the dermal compartment of the skin, existing in a specialized dermal depot and displaying dynamic changes in size during tissue homeostasis. However, the roles of adipocytes in cutaneous biology and disease are not well understood. Traditionally, adipocytes within tissues were thought to act as reservoirs of energy, as thermal, or as structural support. In this review, we discuss recent studies revealing the cellular basis of the dynamic development and regenerative capacity of dermal adipocytes associated with the hair cycle and following injury. We discuss and speculate on potential roles of dermal adipocytes in cutaneous biology with an emphasis on communication during hair follicle growth and wound healing. Finally, we explore how alterations in the dermal adipose tissue may support clinical manifestations of cutaneous diseases such as lipodystrophy, obesity, and alopecia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.