ArticleBMJ case reports2014
Opana ER abuse and thrombotic thrombocytopenic purpura (TTP)-like illness: a rising risk factor in illicit drug users.
Article in BMJ case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Post-traumatic thrombotic microangiopathy: What trauma surgeons need to know?Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2021Review
- Impact of Opioid Use in Hematological Malignancies: Clinical, Immunological and Concomitant Aspects.Journal of hematology · 2020Review
- Opana-induced thrombotic microangiopathy masquerading as thrombotic thrombocytopenic purpura.Oxford medical case reports · 2017Article
- Opiate Injection-associated Infective Endocarditis in the Southeastern United States.The American journal of the medical sciences · 2016Article
- Relapsing thrombotic microangiopathy and intravenous sustained-release oxycodone.Clinical kidney journal · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the case of a 22 year-old-woman who presented with upper extremity cellulitis secondary to an infiltration of illicit intravenous drug use. She confessed to the intravenous use of Opana ER (an extended release oral formulation of oxymorphone) which is an opioid drug approved only for oral use. She was found to have clinical evidence of profound thrombotic microangiopathy which resulted due to the intravenous use of Opana ER. She showed full clinical improvement after withholding drug and supportive clinical care. Recent report of Opana ER intravenous abuse was published from Tennessee county and has now been increasingly recognised as one of the causes of thrombocytopenia which mimicks clinically as thrombotic thrombocytopenic purpura. Physicians should be aware of this association as the lack of familiarity to this can pose serious management dilemmas for our patients (especially the polysubstance abusers).
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Registered trials
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