ArticleThe Journal of cell biology1988
Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells.
Article in The Journal of cell biology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- CK7 expression associates with the location, differentiation, lymph node metastasis, and the Dukes' stage of primary colorectal cancers.Journal of Cancer · 2019Article
- The human keratins: biology and pathology.Histochemistry and cell biology · 2008Review
- Gene expression profiling of noninvasive primary urothelial tumours using microarrays.British journal of cancer · 2005Article
- Article
- Transcription factor Sp1 activates involucrin promoter activity in non-epithelial cell types.The Biochemical journal · 1999Article
- Protein and mRNA expression of simple epithelial keratins in normal, dysplastic, and malignant oral epithelia.The American journal of pathology · 1994Article
- Low nucleotide diversity in man.Genetics · 1991Article
- Retinoid-mediated transcriptional regulation of keratin genes in human epidermal and squamous cell carcinoma cells.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- Assembly of amino-terminally deleted desmin in vimentin-free cells.The Journal of cell biology · 1990Article
- Regulated expression of vimentin cDNA in cells in the presence and absence of a preexisting vimentin filament network.The Journal of cell biology · 1990Article
- In vitro posttranslational modification of lamin B cloned from a human T-cell line.Molecular and cellular biology · 1990Article
- Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control.Molecular and cellular biology · 1989Article
- Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanisms for initiation and assembly of intermediate filaments.The Journal of cell biology · 1989Article
- Proteomic analysis of cytokeratin isoforms uncovers association with survival in lung adenocarcinoma.Neoplasia (New York, N.Y.)Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simple epithelial cells synthesize a different set of keratins than epidermal cells. In experiments reported in this manuscript, we show that the base level of keratin expression in simple epithelial cells is variable for different cell types, and that, in some simple epithelia, this level can be upregulated by increasing the exposure of cells to retinoids, but not glucocorticoids or estradiol. To elucidate the molecular mechanisms underlying simple epithelial keratin gene regulation, we have isolated and characterized a human gene encoding the simple epithelial keratin K7. By examining the possible regulatory elements of this gene and by investigating the behavior of this gene introduced transiently into simple epithelial cells, we have uncovered a possible basis for the differential expression of epidermal and simple epithelial keratin genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.