ArticleHealth affairs (Project Hope)2014
Prevention and treatment produced large decreases in HIV incidence in a model of people who inject drugs.
Article in Health affairs (Project Hope), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- A Review of Network Models for HIV Spread.Journal of acquired immune deficiency syndromes (1999) · 2025Pooled it
- Nurse Practitioner-Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2022Article
- Article
- Modeling the Impact of Social Determinants of Health on HIV.AIDS and behavior · 2021Article
- A review of network simulation models of hepatitis C virus and HIV among people who inject drugs.The International journal on drug policy · 2021Review
- Psychometric Data Linking Across HIV and Substance Use Cohorts.AIDS and behavior · 2020Article
- Projecting the impact of equity-based preexposure prophylaxis implementation on racial disparities in HIV incidence among MSM.AIDS (London, England) · 2020Article
- Opioid agonist treatment scale-up and the initiation of injection drug use: A dynamic modeling analysis.PLoS medicine · 2019Article
- Systems Modeling to Advance the Promise of Data Science in Epidemiology.American journal of epidemiology · 2019Article
- Article
- Potential drivers of HIV acquisition in African-American women related to mass incarceration: an agent-based modelling study.BMC public health · 2018Article
- Integrated Bio-behavioral Approach to Improve Adherence to Pre-exposure Prophylaxis and Reduce HIV Risk in People Who Use Drugs: A Pilot Feasibility Study.AIDS and behavior · 2018Article
- HIV/AIDS and the African-American Community 2018: a Decade Call to Action.Journal of racial and ethnic health disparities · 2018Article
- Integrated Models of Care for Individuals with Opioid Use Disorder: How Do We Prevent HIV and HCV?Current HIV/AIDS reports · 2018Review
- Agent-Based Modeling in Public Health: Current Applications and Future Directions.Annual review of public health · 2018Review
- Measuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users.AIDS and behavior · 2018Article
- Network Viral Load: A Critical Metric for HIV Elimination.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Exploring the Use of Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among High-Risk People Who Use Drugs in Treatment.Frontiers in public health · 2018Article
- Article
- Rare diseases under different levels of economic analysis: current activities, challenges and perspectives.RMD open · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
In the United States, people who inject drugs continue to be at greatly increased risk of HIV infection. To estimate the effectiveness of various prevention scenarios, we modeled HIV transmission in a dynamic network of drug users and people who did not use drugs that was based on the New York Metropolitan Statistical Area population. We compared the projected HIV incidence in 2020 and 2040 if current approaches continue to be used to the incidence if one or more of the following hypothetical interventions were applied: increased HIV testing, improved access to substance abuse treatment, increased use of needle and syringe programs, scaled-up treatment as prevention, and a "high impact" combination scenario, consisting of all of the strategies listed above. No strategy completely eliminated HIV transmission. The high-impact combination strategy produced the largest decrease in HIV incidence-a 62 percent reduction compared to the status quo. Our results suggest that increased resources for and investments in multiple HIV prevention approaches will be required to eliminate HIV transmission among people who inject drugs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.