ArticleMethods in molecular biology (Clifton, N.J.)2014
Selecting targets from eukaryotic parasites for structural genomics and drug discovery.
Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.Acta crystallographica. Section F, Structural biology communications · 2015Article
- Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP.Acta crystallographica. Section F, Structural biology communications · 2015Article
- Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP.Acta crystallographica. Section F, Structural biology communications · 2015Article
- Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.Acta crystallographica. Section F, Structural biology communications · 2015Article
- Cystoisospora suis - A Model of Mammalian Cystoisosporosis.Frontiers in veterinary science · 2015Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The selection of targets is the first step for any structural genomics project. The application of structural genomics approaches to drug discovery also starts with the selection of targets. Here, three protocols are described that were developed to select targets from eukaryotic pathogens. These protocols could also be applied to other drug discovery projects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.