Evidence map›Paper›PMID 24590636›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014

Randomized, controlled trial of yoga in women with breast cancer undergoing radiotherapy.

Kavita D Chandwani, George Perkins, Hongasandra Ramarao Nagendra, Nelamangala V Raghuram, Amy Spelman, Raghuram Nagarathna, Kayla Johnson, Adoneca Fortier, Banu Arun, Qi Wei and 6 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04457895 (A Randomized, Open-labelled, Controlled Trial Evaluating the Efficacy of a Physical Therapy-yoga-patient Educational Program for Breast Cancer Patients With Pain Due to Hormonal Therapy Treatment.), which is not on this map. Cited by 115 papers, 28 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 28 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04457895 narecruitingnot on this mapstarted 2021, after this paper: background citation

A Randomized, Open-labelled, Controlled Trial Evaluating the Efficacy of a Physical Therapy-yoga-patient Educational Program for Breast Cancer Patients With Pain Due to Hormonal Therapy Treatment.

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2021 to 2028Enrolled108ConditionsBreast CancerArmseducational yoga program, no intervention
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 28 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of yoga on depressive symptoms in breast cancer patients: a meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  5. Yoga for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025
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  15. Impact on fatigue of different types of physical exercise during adjuvant chemotherapy and radiotherapy in breast cancer: systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  16. Exercise Therapy and Radiation Therapy for Cancer: A Systematic Review.International journal of radiation oncology, biology, physics · 2021
    Pooled it
  17. Effects of exercise on the quality of life in breast cancer patients: a systematic review of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
  18. Pooled it
  19. Salute to the sun: a new dawn in yoga therapy for breast cancer.Journal of medical radiation sciences · 2017
    Pooled it
  20. Guideline

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kavita D ChandwaniKavita D. Chandwani, University of Rochester Medical Center, Rochester, NY; Kavita D. Chandwani, George Perkins, Amy Spelman, Kayla Johnson, Adoneca Fortier, Banu Arun, Qi Wei, Robin Haddad, Janet Scheetz, Alejandro Chaoul, and Lorenzo Cohen, The University of Texas MD Anderson Cancer Center, Houston, TX; G. Stephen Morris, St. Jude Children's Research Hospital, Memphis, TN; Hongasandra Ramarao Nagendra, Nelamangala V. Raghuram, Raghuram Nagarathna, Swami Vivekananda Yoga Anusandhana Samsthana, Bengaluru, India; and Clemens Kirschbaum, Technical University of Dresden, Dresden, Germany.
George Perkins
Hongasandra Ramarao Nagendra
Nelamangala V Raghuram
Amy Spelman
Raghuram Nagarathna
Kayla Johnson
Adoneca Fortier
Banu Arun
Qi Wei
Clemens Kirschbaum
Robin Haddad
G Stephen Morris
Janet Scheetz
Alejandro Chaoul
Lorenzo Cohen

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Yoga for women with breast cancer undergoing radiotherapyR01CA138800 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2010 to 2015
$4.1M
Biobehavioral Effects of Yoga During Cancer TreatmentR21CA102385 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COHEN, LORENZO · 2005 to 2007
$511k
NCI NIH HHS CA016672NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA138800NCI NIH HHS R01CA138800NCI NIH HHS R21 CA102385NCI NIH HHS R21CA102385
6 · The paper itself

Abstract

purposePrevious research incorporating yoga (YG) into radiotherapy (XRT) for women with breast cancer finds improved quality of life (QOL). However, shortcomings in this research limit the findings. PATIENTS AND

methodsPatients with stages 0 to III breast cancer were recruited before starting XRT and were randomly assigned to YG (n = 53) or stretching (ST; n = 56) three times a week for 6 weeks during XRT or waitlist (WL; n = 54) control. Self-report measures of QOL (Medical Outcomes Study 36-item short-form survey; primary outcomes), fatigue, depression, and sleep quality, and five saliva samples per day for 3 consecutive days were collected at baseline, end of treatment, and 1, 3, and 6 months later.

resultsThe YG group had significantly greater increases in physical component scale scores compared with the WL group at 1 and 3 months after XRT (P = .01 and P = .01). At 1, 3, and 6 months, the YG group had greater increases in physical functioning compared with both ST and WL groups (P < .05), with ST and WL differences at only 3 months (P < .02). The group differences were similar for general health reports. By the end of XRT, the YG and ST groups also had a reduction in fatigue (P < .05). There were no group differences for mental health and sleep quality. Cortisol slope was steepest for the YG group compared with the ST and WL groups at the end (P = .023 and P = .008) and 1 month after XRT (P = .05 and P = .04).

conclusionYG improved QOL and physiological changes associated with XRT beyond the benefits of simple ST exercises, and these benefits appear to have long-term durability.

Indexed as

Quality of LifeYogaAdultAgedBreast NeoplasmsDepressionDyssomniasFatigueFemaleHumansHydrocortisoneMiddle AgedMuscle Stretching ExercisesSalivaHydrocortisone

Identifiers

PMID24590636
PMCPMC3965260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.