ArticleApplied health economics and health policy2014
Variation in the spillover effects of illness on parents, spouses, and children of the chronically ill.
Article in Applied health economics and health policy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- A Systematic Review of Methods Used by Pediatric Cost-Utility Analyses to Include Family Spillover Effects.PharmacoEconomics · 2024Pooled it
- Validation and reliability of the Italian versions of the Food Allergy Quality of Life -Parental Burden (FAQL-PB) and -Parent Form 10 (FAQLQ-PF10) Questionnaires.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Children's disability and caregivers' health-related quality of life in Australia: A nationwide longitudinal study.European journal of pediatrics · 2026Article
- Evolving Food Allergy Clinical Trials to Become More Patient-Centered.The journal of allergy and clinical immunology. In practice · 2025Review
- Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults.Children (Basel, Switzerland) · 2025Article
- On spillovers in economic evaluations: definition, mapping review and research agenda.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Review
- Article
- Quality of Life, Physical and Mental Health, and Economic Evaluation of Family Caregivers of Chronic Dependent Children: INFAPRINT Cohort Study Protocol.International journal of environmental research and public health · 2023Article
- Exploring the relationship between functional limitations of the older adults and the health-related quality of life of their spouse in Shaanxi Province, China.Health and quality of life outcomes · 2021Article
- The scope of carer effects and their inclusion in decision-making: a UK-based Delphi study.BMC health services research · 2021Article
- Family-level impact of genetic testing: integrating health economics and ethical, legal, and social implications.Personalized medicine · 2021Article
- What's the Cost? Measuring the Economic Impact of Pediatric Sepsis.Frontiers in pediatrics · 2021Article
- Impact of hereditary pancreatitis on patients and their families.Journal of genetic counseling · 2020Article
- Health-related quality of life in neonates and infants: a conceptual framework.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Does the child's health influence the caregiver's health using the EQ-5D instruments?The South African journal of physiotherapy · 2020Article
- Expanding the Scope of Costs and Benefits for Economic Evaluations in Health: Some Words of Caution.PharmacoEconomics · 2019Article
- Parental Health Spillover in Cost-Effectiveness Analysis: Evidence from Self-Harming Adolescents in England.PharmacoEconomics · 2019Article
- Measuring Health Spillover Effects in Caregivers of Children with Autism Spectrum Disorder: A Comparison of the EQ-5D-3L and SF-6D.PharmacoEconomics · 2019Article
- Family and Caregiver Spillover Effects in Cost-Utility Analyses of Alzheimer's Disease Interventions.PharmacoEconomics · 2019Article
- Quantifying Family Spillover Effects in Economic Evaluations: Measurement and Valuation of Informal Care Time.PharmacoEconomics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundGiven the broad scope of the spillover effects of illness, it is important to characterize the variability in these outcomes to identify relationship types in which secondary impacts of illness are particularly important to include in health economic evaluations. PURPOSE: To examine heterogeneity in spillover effects of chronic conditions on family members by type of familial relationship with patient.
methodsAdults (aged ≥18 years) and adolescents (aged 13-17 years) who had a parent, spouse, or child in their household with a chronic condition (Alzheimer's disease/dementia, arthritis, cancer, or depression) were recruited from a US national panel to participate in an on-line survey. Respondents were asked to rate the spillover effect of their family member's illness on their own health on a 0-100 scale, with lower scores indicating greater spillover. Regression analysis was used to evaluate the association between rating scale scores and relationship with an ill family member (ill parent, child, or spouse) for each illness separately, controlling for caregiving responsibility and the health status of the ill family member.
results1,267 adults and 102 adolescents met inclusion criteria. In adjusted analyses, having a sick child was significantly (p < 0.05) associated with lower rating scale scores compared with having a spouse with the same condition (cancer: -24.2; depression -9.7). Having a non-elderly or elderly adult parent with a condition, compared with a spouse, was significantly associated with lower rating scale scores for arthritis (-3.8) and depression (-5.3), but not for Alzheimer's disease/dementia or cancer.
conclusionsThe impact of illness on family members, measured with a rating scale, varies by relationship type for certain illnesses. Having a child with cancer, a parent with arthritis, or either with depression, is significantly associated with greater spillover, compared with having a spouse with one of these conditions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.