ArticleEnvironmental science and pollution research international2015
Effect of a thymol application on olfactory memory and gene expression levels in the brain of the honeybee Apis mellifera.
Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Review
- Review
- Use of Thymol inInsects · 2022Article
- Sub-lethal effects of the consumption of Eupatorium buniifolium essential oil in honeybees.PloS one · 2020Article
- Thymol Affects Congruency Between Olfactory and Gustatory Stimuli in Bees.Scientific reports · 2019Article
- The terpenes of leaves, pollen, and nectar of thyme (Thymus vulgaris) inhibit growth of bee disease-associated microbes.Scientific reports · 2018Article
- Prolonged effects of in-hive monoterpenoids on the honey bee Apis mellifera.Ecotoxicology (London, England) · 2016Article
- Crop protection, environment, health, and biodiversity: observations and outlook.Environmental science and pollution research international · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Essential oils are used by beekeepers to control the Varroa mites that infest honeybee colonies. So, bees can be exposed to thymol formulations in the hive. The effects of the monoterpenoid thymol were explored on olfactory memory and gene expression in the brain of the honeybee. In bees previously exposed to thymol (10 or 100 ng/bee), the specificity of the response to the conditioned stimulus (CS) was lost 24 h after learning. Besides, the octopamine receptor OA1 gene Amoa1 showed a significant decrease of expression 3 h after exposure with 10 or 100 ng/bee of thymol. With the same doses, expression of Rdl gene, coding for a GABA receptor subunit, was not significantly modified but the trpl gene was upregulated 1 and 24 h after exposure to thymol. These data indicated that the genes coding for the cellular targets of thymol could be rapidly regulated after exposure to this molecule. Memory and sensory processes should be investigated in bees after chronic exposure in the hive to thymol-based preparations.
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Registered trials
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