ArticleVirchows Archiv : an international journal of pathology2014
Variation in reporting of cancer extent and benign histology in prostate biopsies among European pathologists.
Article in Virchows Archiv : an international journal of pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of incidental prostate cancer: A systematic review of autopsy studies.International journal of cancer · 2015Pooled it
- Using radiomics model for predicting extraprostatic extension with PSMA PET/CT studies: a comparative study with the Mehralivand grading system.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Unexpectedly high variability in determining tumour extent in prostatic biopsies: implications for active surveillance.Histopathology · 2025Article
- Handling and reporting of transperineal template prostate biopsy in Europe: a web-based survey by the European Network of Uropathology (ENUP).Virchows Archiv : an international journal of pathology · 2018Article
- The combination of histological prostate atrophy and inflammation is associated with lower risk of prostate cancer in biopsy specimens.Prostate cancer and prostatic diseases · 2017Article
- Greater extent of prostate inflammation in negative biopsies is associated with lower risk of prostate cancer on repeat biopsy: results from the REDUCE study.Prostate cancer and prostatic diseases · 2016Article
- Article
- Gleason underestimation is predicted by prostate biopsy core length.World journal of urology · 2015Article
- Prognostic histopathological and molecular markers on prostate cancer needle-biopsies: a review.BioMed research international · 2014Review
- Predictive criteria of insignificant prostate cancer: what is the correspondence of linear extent to percentage of cancer in a single core?International braz j urol : official journal of the Brazilian Society of UrologyArticle
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10 authors.
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Abstract
It is not known how uropathologists currently report histopathological features of prostate biopsies such as core length, tumor extent, perineural invasion, and non-tumor-associated features such as inflammation and hyperplasia in needle biopsies. A web-based survey was distributed among 661 members of the European Network of Uropathology. Complete replies were received from 266 pathologists in 22 European countries. Total core lengths were reported by 64 %. The numbers of cores positive for cancer was given by 79 %. Linear cancer extent was reported by 81 %, most often given in millimeters for each core (53 %) followed by the estimation of percentage of cancer in each core (40 %). A gap of benign tissue between separate cancer foci in a single core would always be subtracted by 48 % and by 63 % if cancer foci were minute and widely separated. Perineural invasion was reported by 97 %. Fat invasion by tumor was interpreted as extraprostatic extension by 81 %. Chronic and active/acute inflammation was always reported by 32 and 56 % but only if pronounced by 54 and 39 %, respectively. While most (79 %) would never diagnose benign prostatic hyperplasia on needle biopsy, 21 % would attempt to make this diagnosis. Reporting practices for prostate biopsies are variable among European pathologists. The great variation in some methodologies used suggests a need for further international consensus, in order for retrospective data to be comparable between different institutions.
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