Trial reportBMJ open2014
Validity of self-reported hysterectomy: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).
Trial report in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Correlates of hysterectomy in low- and middle-income countries: a systematic review.Journal of global health · 2026Pooled it
- A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer.International journal of cancer · 2016Pooled it
- Association of hysterectomy and invasive epithelial ovarian and tubal cancer: a cohort study within UKCTOCS.BJOG : an international journal of obstetrics and gynaecology · 2022Trial
- Trial
- All-cause mortality after self-reported vs. hospital-reported gynecological surgery: The HUNT study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Education level is associated with the occurrence and timing of hysterectomy: A cohort study of Canadian women.Acta obstetricia et gynecologica Scandinavica · 2024Article
- The impact of adjusting for hysterectomy prevalence on cervical cancer incidence rates and trends among women aged 30 years or older-United States, 2001-2019.American journal of epidemiology · 2024Article
- Association of hysterectomy with nonalcoholic fatty liver disease among US women.Lipids in health and disease · 2024Article
- Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany.BMC public health · 2023Article
- Higher prevalence of hysterectomy among rural women than urban women: Implications for measures of disparities in uterine and cervical cancers.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2022Article
- US hysterectomy prevalence by age, race and ethnicity from BRFSS and NHIS: implications for analyses of cervical and uterine cancer rates.Cancer causes & control : CCC · 2022Article
- Validity of self-reported diagnoses of gynaecological and breast cancers in a prospective cohort study: the Japan Nurses' Health Study.BMJ open · 2021Article
- Hysterectomy and Bilateral Salpingo-Oophorectomy: Variations by History of Military Service and Birth Cohort.The Gerontologist · 2016Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo evaluate the validity of self-reported hysterectomy against the gold standard of uterine visualisation using pelvic ultrasound.
designProspective cohort study.
settingUK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) based in 13 National Health Service (NHS) Trusts in England, Wales and Northern Ireland.
participantsBetween April 2001 and October 2005, 48 215 postmenopausal women aged 50-74 randomised to the ultrasound screening arm of UKCTOCS underwent the first (initial) scan on the trial.
interventionsAt recruitment, the women completed a recruitment questionnaire (RQ) which included previous hysterectomy. The sonographer asked each woman regarding previous hysterectomy (interview format, IF) prior to the scan. At the scan, in addition to ovarian morphology, endometrial thickness (ET)/endometrial abnormality were captured if the uterus was visualised at the scan. OUTCOME MEASURES: Self-reported hysterectomy at RQ or IF was compared to ultrasound data on ET/endometrial abnormality (as surrogate uterine visualisation markers) on the first (initial) scan.
resultsOf 48 215 women, 3 had congenital uterine agenesis and 218 inconclusive results. The uterus was visualised in 39 121 women. 8871 self-reported hysterectomy at RQ, 8641 at IF and 8487 at both. The uterus was visualised in 39 123, 39 353 and 38 969 women not self-reporting hysterectomy at RQ, IF or both. Validity, sensitivity, specificity, positive predictive value and negative predictive value of using RQ alone, IF or both RQ/IF were 99.6%, 98.9%, 99.7%, 98.9% and 99.7%; 98.9%, 98.4%, 99.1%, 95.9% and 99.7%; 99.8%, 99.6%, 99.9%, 99.4% and 99.9%, respectively.
conclusionsSelf-reported hysterectomy is a highly accurate and valid source for studying long-term associations of hysterectomy with disease onset.
trial registrationInternational Standard Randomised Controlled Trial Number (ISRCTN)-22488978.
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