Evidence map›Paper›PMID 24589717›Full record

ArticlemAbs

Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.

Juan Carlos Almagro, Gary L Gilliland, Felix Breden, Jamie K Scott, Devin Sok, Matthias Pauthner, Janice M Reichert, Gustavo Helguera, Raiees Andrabi, Robert Mabry and 14 more

Open access · goldAbstract readConference Proceedings
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 19 institutions in 9 countries.

Juan Carlos AlmagroCTI-Boston, Pfizer; Boston, MA USA.
Gary L GillilandJanssen Research & Development, LLC; Spring House, PA USA.
Felix BredenSimon Fraser University; Burnaby, BC CA.
Jamie K ScottSimon Fraser University; Burnaby, BC CA.
Devin SokThe Scripps Research Institute; La Jolla, CA USA.
Matthias PauthnerThe Scripps Research Institute; La Jolla, CA USA.
Janice M ReichertReichert Biotechnology Consulting, LLC; Framingham, MA USA.
Gustavo HelgueraCONICET; Laboratorio Biotecnología Farmacéutica; Instituto de Biología y Medicina Experimental, IBYME; Ciudad Autónoma de Buenos Aires, Argentina.
Raiees AndrabiThe Scripps Research Institute; La Jolla, CA USA.
Robert MabryAdimab, LLC; Lebanon, NH USA.
Mathieu BléryInnate Pharma; Marseille, France.
James E VossThe Scripps Research Institute; La Jolla, CA USA.
Juha LaurénRegeneron Pharmaceuticals, Inc.; Tarrytown, NY USA.
Lubna AbuqayyasAmgen, Thousand Oaks, CA, USA.
Stefan BarghornAbbVie; Ludwigshafen, Germany.
Eshel Ben-JacobTel Aviv University, Tel Aviv, Israel.
James E CroweVanderbilt University Medical Center, Nashville, TN, USA.
James S HustonHuston BioConsulting, LLC; Newton, MA, USA.
Stephen Albert JohnstonArizona State University; Phoenix, AZ USA.
Eric KraulandAdimab, LLC; Lebanon, NH USA.
Fridtjof Lund-JohansenOslo University Hospital; Oslo, Norway.
Wayne A MarascoDana-Farber Cancer Center; Boston, MA USA.
Paul W H I ParrenGenmab; Utrecht, The Netherlands.
Kai Y XuUniversity of Maryland; Baltimore, MD USA.
Scripps Research Institute · USAdimab (United States) · USSimon Fraser University · CAAmgen (United States) · USBioConsult SH (Germany) · DECentro Científico Tecnológico - Tucumán · ARDana-Farber Cancer Institute · USFramingham State University · USGenmab (United States) · USInnate Pharma (France) · FRJanssen (Belgium) · BELudwigshafen University of Business and Society · DEOslo University Hospital · NOPfizer (United States) · USPhoenix (United States) · USRegeneron (United States) · USTel Aviv University · ILUniversity of Maryland, Baltimore · USVanderbilt University Medical Center · US

Funding

Origin of Antibodies with Long CDR-H3 Loops in HIV Infection & Autoimmune DiseaseR21AI076176 · NIAID · SIMON FRASER UNIVERSITY · PI BREDEN, FELIX J, SCOTT, JAMIE KATHLEEN · 2008 to 2009
$334k
NIAID NIH HHS R21 AI076176
6 · The paper itself

Abstract

The 24th Antibody Engineering & Therapeutics meeting brought together a broad range of participants who were updated on the latest advances in antibody research and development. Organized by IBC Life Sciences, the gathering is the annual meeting of The Antibody Society, which serves as the scientific sponsor. Preconference workshops on 3D modeling and delineation of clonal lineages were featured, and the conference included sessions on a wide variety of topics relevant to researchers, including systems biology; antibody deep sequencing and repertoires; the effects of antibody gene variation and usage on antibody response; directed evolution; knowledge-based design; antibodies in a complex environment; polyreactive antibodies and polyspecificity; the interface between antibody therapy and cellular immunity in cancer; antibodies in cardiometabolic medicine; antibody pharmacokinetics, distribution and off-target toxicity; optimizing antibody formats for immunotherapy; polyclonals, oligoclonals and bispecifics; antibody discovery platforms; and antibody-drug conjugates.

Indexed as

AnimalsAntibodiesDirected Molecular EvolutionDrug DesignHumansImmunotherapyNeoplasmsProtein EngineeringSocieties, ScientificSystems BiologyAntibodiesantibody-drug conjugateantibody therapeutics,bispecific antibodiesprotein scaffolds

Identifiers

PMID24589717
PMCPMC4011904
OpenAlexW1997514113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.