Evidence map›Paper›PMID 24587990›Full record

ReviewBioMed research international2014

Oxidative stress, prooxidants, and antioxidants: the interplay.

Anu Rahal, Amit Kumar, Vivek Singh, Brijesh Yadav, Ruchi Tiwari, Sandip Chakraborty, Kuldeep Dhama

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 606 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
606citing papers in PubMed, 1 pooled it
66.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

606 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,685 citations in OpenAlex.

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  15. Gill Adaptation of the Hong Kong Catfish (Ecology and evolution · 2026
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546 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anu RahalDepartment of Veterinary Pharmacology and Toxicology, Uttar Pradesh Pandit, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwa Vidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.
Amit KumarDepartment of Veterinary Microbiology and Immunology, Uttar Pradesh Pandit, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwa Vidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.
Vivek SinghDepartment of Animal Husbandry, Kuchaman, Rajasthan 341508, India.
Brijesh YadavDepartment of Veterinary Physiology, Uttar Pradesh Pandit, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwa Vidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.
Ruchi TiwariDepartment of Veterinary Microbiology and Immunology, Uttar Pradesh Pandit, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwa Vidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.ORCID 0000-0001-7763-5547
Sandip ChakrabortyAnimal Resources Development Department, Pt. Nehru Complex, Agartala 799006, India.ORCID 0000-0002-0175-5320
Kuldeep DhamaDivision of Pathology, Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, India.ORCID 0000-0001-7469-4752
Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · INIndian Veterinary Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an imbalance between the prooxidants and antioxidants in the body. For the last two decades, oxidative stress has been one of the most burning topics among the biological researchers all over the world. Several reasons can be assigned to justify its importance: knowledge about reactive oxygen and nitrogen species production and metabolism; identification of biomarkers for oxidative damage; evidence relating manifestation of chronic and some acute health problems to oxidative stress; identification of various dietary antioxidants present in plant foods as bioactive molecules; and so on. This review discusses the importance of oxidative stress in the body growth and development as well as proteomic and genomic evidences of its relationship with disease development, incidence of malignancies and autoimmune disorders, increased susceptibility to bacterial, viral, and parasitic diseases, and an interplay with prooxidants and antioxidants for maintaining a sound health, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue.

Indexed as

AntioxidantsHumansOxidation-ReductionOxidative StressReactive Nitrogen SpeciesReactive Oxygen SpeciesAntioxidantsReactive Nitrogen SpeciesReactive Oxygen Species

Identifiers

PMID24587990
PMCPMC3920909
OpenAlexW2082221119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.