Evidence map›Paper›PMID 24587979›Full record

ArticleCurrent pathobiology reports2014

Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain.

Spencer W Crowder, Daniel A Balikov, Yu-Shik Hwang, Hak-Joon Sung

Open access · bronzeAbstract read
In one paragraph

Article in Current pathobiology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Tumour Stem Cells in Breast Cancer.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Hypoxia in the Initiation and Progression of Neuroblastoma Tumours.International journal of molecular sciences · 2019
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Spencer W CrowderDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA ; Center for Stem Cell Biology, Vanderbilt University Medical Center, Nashville, TN, USA.
Daniel A BalikovDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA ; Center for Stem Cell Biology, Vanderbilt University Medical Center, Nashville, TN, USA.
Yu-Shik HwangDepartment of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University, Seoul, South Korea.
Hak-Joon SungDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA ; Center for Stem Cell Biology, Vanderbilt University Medical Center, Nashville, TN, USA ; Department of Maxillofacial Biomedical Engineering, School of Dentistry, Kyung Hee University, Seoul, South Korea.
Kyung Hee University · KRVanderbilt University · USVanderbilt University Medical Center · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Neurovascular Unit on a Chip: Regional Chemical Communication, Drug and Toxin ResponsesUH3TR000491 · NCATS · VANDERBILT UNIVERSITY · PI GHOSH, CHAITALI, JANIGRO, DAMIR · 2014 to 2016
$3.8M
Neurovascular Unit on a Chip: Chemical Communication, Drug and Toxin ResponsesUH2TR000491 · NCATS · VANDERBILT UNIVERSITY · PI JANIGRO, DAMIR, NISWENDER, KEVIN D · 2012 to 2013
$2.2M
NCATS NIH HHS UH2 TR000491NCATS NIH HHS UH3 TR000491NIGMS NIH HHS T32 GM007347
6 · The paper itself

Abstract

Over the last fifteen years, basic science and clinical studies have aimed to identify cancer stem cells (CSCs) in multiple types of cancer in order to unravel their mechanistic roles in cancer recurrence for therapeutic exploitation. Exposure of cells and tissues to hypoxia, or sub-atmospheric concentrations of oxygen (< 21% O

Indexed as

brain cancerbreast cancercancercancer recurrenceCancer stem cellschemoresistanceglioblastomahypoxiahypoxia inducible factor (HIF)metastasisneoplasiaoxygen tensionstem cellstumor-initiating cells

Identifiers

PMID24587979
PMCPMC3935368
OpenAlexW1993411642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.