ReviewAdvances in wound care2013
Clinical Impact Upon Wound Healing and Inflammation in Moist, Wet, and Dry Environments.
Review in Advances in wound care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03907111 (Develop the Biologic-fibrotic Dressing on War Open Bleeding Wounds for Hemostasis.), which is not on this map. Cited by 157 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Develop the Biologic-fibrotic Dressing on War Open Bleeding Wounds for Hemostasis.
Who cites it
157 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of oxidised regenerated cellulose/collagen dressings versus standard of care over multiple wound types: A systematic review and meta-analysis.International wound journal · 2022Pooled it
- Clinical efficacy of chitosan-based hydrocolloid dressing in the treatment of chronic refractory wounds.International wound journal · 2022Trial
- Efficacy of Rhino-Protect ointment after endoscopic sinus surgery: a prospective, randomized, multicenter study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Trial
- The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial.BMC complementary and alternative medicine · 2017Trial
- Enzyme responsive antimicrobial hyaluronan-nanocellulose hybrid wound dressings for the treatment of infected wounds.Bioactive materials · 2026Article
- Treatment of Pediatric Fingertip Amputations by Chest and Palm Subcutaneous Pocket Techniques.Plastic and reconstructive surgery. Global open · 2026Article
- Article
- The First Reported Clinical Outcomes of a Next Generation Five-Layer Foam Dressing for Exudate Management: A Retrospective, Real World, Cohort Analysis From the United States.International wound journal · 2026Article
- Alginate and Chitosan-Based Hydrogels for the Treatment of Radiation Dermatitis.International wound journal · 2026Review
- Evidence-Based Translational Strategy of Medicated Topical Gel for Diabetic Wound Management.Pharmaceutics · 2026Article
- Alginate-Based Biomaterials: From Fundamental "Egg-Box" Chemistry to Diverse Biomedical and Metabolic Management of Obesity and Diabetes.Gels (Basel, Switzerland) · 2026Review
- A transparent osmotic wound dressing ATKPAD promotes the healing process and regulates hypoxia-dependent inflammatory responses.Scientific reports · 2026Article
- A Biomimetic NAC-Loaded PCL/Modified Chitosan/dECM Fibrous Scaffold for Accelerating Diabetic Wound Healing and Minimizing Scarring.Polymers · 2026Article
- An immunomodulatory hydrogel featuring antibacterial and ROS-scavenging functions for enhanced burn wound healing.Journal of nanobiotechnology · 2026Article
- Immunomodulatory role of decellularized extracellular matrix in skin wound healing.Materials today. Bio · 2026Review
- Open Porous Microenvironment-regulatory Microspheres Loaded with Curcumin@BSA NPs/BMSCs for Diabetic Wound Treatment.Theranostics · 2026Article
- Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers.Frontiers in bioengineering and biotechnology · 2026Review
- Fractional COClinical, cosmetic and investigational dermatology · 2026Article
- Curcumin-berberine ointment based on multifunctional carrier accelerates wound healing in a translational porcine model of tail-biting injuries: a controlled study against oxytetracycline.Frontiers in pharmacology · 2026Article
- Biomimetic aligned bacterial cellulose dressing containing polydeoxyribonucleotide for promoting wound healing.Bioactive materials · 2025Article
97 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
significanceSuccessful treatment of wounds relies on precise control and continuous monitoring of the wound-healing process. Wet or moist treatment of wounds has been shown to promote re-epithelialization and result in reduced scar formation, as compared to treatment in a dry environment. RECENT ADVANCES: By treating wounds in a controlled wet environment, delivery of antimicrobials, analgesics, other bioactive molecules such as growth factors, as well as cells and micrografts, is allowed. The addition of growth factors or transplantation of cells yields the possibility of creating a regenerative wound microenvironment that favors healing, as opposed to excessive scar formation. CRITICAL ISSUES: Although several manufacturers have conceived products implementing the concept of moist wound healing, there remains a lack of commercial translation of wet wound-healing principles into clinically available products. This can only be mitigated by further research on the topic. FUTURE DIRECTIONS: The strong evidence pointing to the favorable healing of wounds in a wet or moist environment compared to dry treatment will extend the clinical indications for this treatment. Further advances are required to elucidate by which means this microenvironment can be optimized to improve the healing outcome.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.