ArticleRadiology and oncology2014
Individual radiosensitivity in a breast cancer collective is changed with the patients' age.
Article in Radiology and oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Breast cancer risk genes affecting individual radiosensitivity.Scientific reports · 2026Article
- Persons with epilepsy have an elevated radiosensitivity, which may be mitigated by folic acid.Journal of neurology · 2026Article
- Ex Vivo Chromosomal Radiosensitivity Testing in Patients with Pathological Germline Variants in Breast Cancer High-Susceptibility GenesCurrent issues in molecular biology · 2023Article
- Article
- Individual Radiosensitivity as a Risk Factor for the Radiation-Induced Acute Radiodermatitis.Life (Basel, Switzerland) · 2021Article
- Predicting chromosome damage in astronauts participating in international space station missions.Scientific reports · 2021Article
- Ex vivo radiosensitivity is increased in non-cancer patients taking valproate.BMC neurology · 2020Article
- Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assays.Biological procedures online · 2020Review
- Rate of individuals with clearly increased radiosensitivity rise with age both in healthy individuals and in cancer patients.BMC geriatrics · 2018Article
- Lethal outcome after pelvic salvage radiotherapy in a patient with prostate cancer due to increased radiosensitivity : Case report and literature review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018Review
- Assessment of Correlation between Chromosomal Radiosensitivity of Peripheral Blood Lymphocytes afterGenome integrity · 2017Article
- Release of growth factors after mechanical and chemical pleurodesis for treatment of malignant pleural effusion: a randomized control study.Radiology and oncology · 2015Article
- Distinct increased outliers among 136 rectal cancer patients assessed by γH2AX.Radiation oncology (London, England) · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndividual radiosensitivity has a crucial impact on radiotherapy related side effects. Our aim was to study a breast cancer collective for its variation of individual radiosensitivity depending on the patients' age. MATERIALS AND
methodsPeripheral blood samples were obtained from 129 individuals. Individual radiosensitivity in 67 breast cancer patients and 62 healthy individuals was estimated by 3-color fluorescence in situ hybridization.
resultsBreast cancer patients were distinctly more radiosensitive compared to healthy controls. A subgroup of 9 rather radiosensitive and 9 rather radio-resistant patients was identified. A subgroup of patients aged between 40 and 50 was distinctly more radiosensitive than younger or older patients.
conclusionsIn the breast cancer collective a distinct resistant and sensitive subgroup is identified, which could be subject for treatment adjustment. Preliminary results indicate that especially in the range of age 40 to 50 patients with an increased radiosensitivity are more frequent and may have an increased risk to suffer from therapy related side effects.
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