ReviewWorld journal of gastroenterology2014
Treatment of gastric cancer.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05299476 (A Single-arm, Open Phase II Trial of CAPOX Combined With Bevacizumab Combined With Tislelizumab in First-line Treatment of PDL1 CPS < 5 Locally Advanced or Metastati Gastroesophageal Adenocarcinoma), which is not on this map. Cited by 358 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single-arm, Open Phase II Trial of CAPOX Combined With Bevacizumab Combined With Tislelizumab in First-line Treatment of PDL1 CPS < 5 Locally Advanced or Metastati Gastroesophageal Adenocarcinoma
Who cites it
358 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effect of Dietary Interventions on Body Composition and Quality of Life in Stomach Cancer Survivors after Gastrectomy: A Systematic Review.Journal of gastrointestinal cancer · 2026Pooled it
- Methodological Quality of Systematic Reviews on Treatments for Gastric Cancer: A Cross-Sectional Study.Digestive surgery · 2026Pooled it
- Gastric cancer radiation therapy: a bibliometric analysis of the scientific literature.Frontiers in oncology · 2025Pooled it
- The role of traditional Chinese medicine in postoperative wound complications of gastric cancer.International wound journal · 2024Pooled it
- Quality of Life Following the Surgical Management of Gastric Cancer Using Patient-Reported Outcomes: A Systematic Review.Current oncology (Toronto, Ont.) · 2024Pooled it
- Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges.Molecular oncology · 2021Pooled it
- Influencing Factors and Effects of Treatment on Quality of Life in Patients With Gastric Cancer-A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Multi-phase hybrid metabolomics framework identifies clinically applicable plasma signatures for early detection of gastric cancer.Nature communications · 2026Article
- Dual Cardiotoxicity of Capecitabine: Coronary Vasospasm and QT Prolongation in a Patient With Gastric Adenocarcinoma.JACC. Case reports · 2026Article
- Gastric cancer patients' survival with neoadjuvant chemotherapy versus direct surgery.Caspian journal of internal medicine · 2026Article
- MiR-668-3p in M2 macrophage-derived exosomes activates autophagy through the ETS1/EGFR axis and promotes cisplatin resistance in gastric cancer.Cancer cell international · 2025Article
- The Efficiency of Plant Extracts in the Prevention of Gastric Cancer: A Systematic Review.Health science reports · 2025Review
- A Histopathological and Surgical Analysis of Gastric Cancer: A Two-Year Experience in a Single Center.Cancers · 2025Article
- CAR T cell therapies in gastrointestinal cancers: current clinical trials and strategies to overcome challenges.Nature reviews. Gastroenterology & hepatology · 2025Review
- Article
- Analysis of risk and prognostic factors for pulmonary metastasis in gastric cancer: a study based on the Surveillance, Epidemiology, and End Results database.Translational cancer research · 2025Article
- Identification of CKAP2 as a Potential Target for Prevention of Gastric Cancer Progression: A Multi-Omics Study.International journal of molecular sciences · 2025Article
- Risk factors for fluorouracil-induced cardiotoxicity in patients with gastrointestinal tumor.Frontiers in cardiovascular medicine · 2025Article
- Gastric cancer peritoneal metastasis: a bibliometric study from 2000 to 2024 using VOSviewer software.Frontiers in oncology · 2025Review
- Quercetin Inhibits Gastric Cancer Progression via FAM198B/MAPK Pathway Modulation.Pharmacogenomics and personalized medicine · 2025Article
298 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The authors focused on the current surgical treatment of resectable gastric cancer, and significance of peri- and post-operative chemo or chemoradiation. Gastric cancer is the 4(th) most commonly diagnosed cancer and the second leading cause of cancer death worldwide. Surgery remains the only curative therapy, while perioperative and adjuvant chemotherapy, as well as chemoradiation, can improve outcome of resectable gastric cancer with extended lymph node dissection. More than half of radically resected gastric cancer patients relapse locally or with distant metastases, or receive the diagnosis of gastric cancer when tumor is disseminated; therefore, median survival rarely exceeds 12 mo, and 5-years survival is less than 10%. Cisplatin and fluoropyrimidine-based chemotherapy, with addition of trastuzumab in human epidermal growth factor receptor 2 positive patients, is the widely used treatment in stage IV patients fit for chemotherapy. Recent evidence supports the use of second-line chemotherapy after progression in patients with good performance status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.