Evidence map›Paper›PMID 24587620›Full record

ReviewWorld journal of gastroenterology2014

A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication.

Elvira Garza-González, Guillermo Ignacio Perez-Perez, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04039412 (Comparison Between Hybrid, Reverse Hybrid, and Non-Bismuth Levofloxacin Quadruple Regimens for Helicobacter Pylori Infection in Egypt), which is not on this map. Cited by 86 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 4 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04039412 phase4completednot on this mapstarted 2018, after this paper: background citation

Comparison Between Hybrid, Reverse Hybrid, and Non-Bismuth Levofloxacin Quadruple Regimens for Helicobacter Pylori Infection in Egypt: A Randomized Controlled Trial

TypeinterventionalSponsorAyman Magd Eldin Mohammad SadekRan2018 to 2019Enrolled330ConditionsHelicobacter Pylori InfectionArmsHybrid regimen, Reverse hybrid regimen, Levofloxacin quadruple regimen
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 209 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Association between atrial fibrillation and Helicobacter pylori.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Low-Abundance and FragmentaryBiomolecules · 2026
    Article
  10. Article
  11. Review
  12. International journal of molecular sciences · 2025
    Review
  13. Article
  14. Article
  15. Review of Methods for DetectionJGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  16. Article
  17. Review
  18. Overcoming the effects of increasing antimicrobial resistance onExpert review of gastroenterology & hepatology · 2024
    Review
  19. Observational
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elvira Garza-GonzálezElvira Garza-González, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Guillermo Ignacio Perez-PerezElvira Garza-González, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Héctor Jesús Maldonado-GarzaElvira Garza-González, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Francisco Javier Bosques-PadillaElvira Garza-González, Héctor Jesús Maldonado-Garza, Francisco Javier Bosques-Padilla, Servicio de Gastroenterología y Departamento de Patología Clínica, Hospital Universitario "Dr. José Eleuterio González" Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Universidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic methods exist to detect infection, and the choice of one method or another depends on several factors, such as accessibility, advantages and disadvantages of each method, cost, and the age of patients. Once H. pylori infection is diagnosed, the clinician decides whether treatment is necessity, according to the patient's clinical condition. Typically, eradication of H. pylori is recommended for treatment and prevention of the infection. Cure rates with the standard triple therapy are acceptable, and effective quadruple therapies, sequential therapies, and concomitant therapies have been introduced as key alternatives to treat H. pylori infection. In this work, we review the main diagnostic methods used to identify H. pylori infection and to confirm eradication of infection. In addition, key factors related to treatment are reviewed.

Indexed as

Anti-Bacterial AgentsBiopsyBreath TestsClarithromycinDrug Resistance, BacterialHelicobacter InfectionsHelicobacter pyloriHumansLymphoma, B-Cell, Marginal ZonePeptic UlcerProbioticsReproducibility of ResultsStomach NeoplasmsStomach UlcerTreatment OutcomeUreaAnti-Bacterial AgentsClarithromycinUreaUreaseConcomitant therapyDiagnosisHelicobacter pyloriHybrid therapySequential therapyTreatment

Identifiers

PMID24587620
PMCPMC3925853
OpenAlexW2016457467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.