Evidence map›Paper›PMID 24587617›Full record

ReviewWorld journal of gastroenterology2014

Helicobacter pylori infection and extragastric disorders in children: a critical update.

Lucia Pacifico, John F Osborn, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Claudio Chiesa

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. JPGN reports · 2025
    Article
  4. Unveiling the prevalence of Helicobacter pylori CagA and VacA virulence markers in Moroccan children and adolescents.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  5. Article
  6. Impact ofDiagnostics (Basel, Switzerland) · 2023
    Review
  7. Antibiotics (Basel, Switzerland) · 2023
    Review
  8. Association BetweenJournal of blood medicine · 2023
    Article
  9. Factors Associated WithInternational journal of public health · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. International journal of general medicine · 2020
    Article
  15. Article
  16. Article
  17. Review
  18. Helicobacter pylori infection increases the risk of adult-onset asthma: a nationwide cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  19. Molecular mimicry inWorld journal of gastroenterology · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucia PacificoLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.
John F OsbornLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.
Valeria TrombaLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.
Sara RomaggioliLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.
Stefano BascettaLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.
Claudio ChiesaLucia Pacifico, Valeria Tromba, Sara Romaggioli, Stefano Bascetta, Department of Pediatrics, Sapienza University of Rome, 324 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (H. pylori) is a highly prevalent, serious and chronic infection that has been associated causally with a diverse spectrum of extragastric disorders including iron deficiency anemia, chronic idiopathic thrombocytopenic purpura, growth retardation, and diabetes mellitus. The inverse relation of H. pylori prevalence and the increase in allergies, as reported from epidemiological studies, has stimulated research for elucidating potential underlying pathophysiological mechanisms. Although H. pylori is most frequently acquired during childhood in both developed and developing countries, clinicians are less familiar with the pediatric literature in the field. A better understanding of the H. pylori disease spectrum in childhood should lead to clearer recommendations about testing for and treating H. pylori infection in children who are more likely to develop clinical sequelae. A further clinical challenge is whether the progressive decrease of H. pylori in the last decades, abetted by modern clinical practices, may have other health consequences.

Indexed as

Helicobacter pyloriAnemia, Iron-DeficiencyAsthmaChildClinical Trials as TopicDiabetes MellitusGrowth DisordersHelicobacter InfectionsHumansHypersensitivityPurpura, Thrombocytopenic, IdiopathicAllergyAsthmaChildrenChronic idiopathic thrombocytopenic purpuraDiabetes mellitusGrowth retardationHelicobacter pyloriIron deficiency anemia

Identifiers

PMID24587617
PMCPMC3925850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.