Observational studyPLoS neglected tropical diseases2014
The association of parasitic infections in pregnancy and maternal and fetal anemia: a cohort study in coastal Kenya.
Observational study in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
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Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Prevalence and predictors of anemia among pregnant women in Ethiopia: Systematic review and meta-analysis.PloS one · 2022Pooled it
- Intestinal parasitic infections and associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Maternal Hookworm Infection and Its Effects on Maternal Health: A Systematic Review and Meta-Analysis.The American journal of tropical medicine and hygiene · 2020Pooled it
- Praziquantel for the treatment of schistosomiasis during human pregnancy.Bulletin of the World Health Organization · 2018Trial
- Evaluating policy guidelines for the prevention and management of anaemia in pregnancy in Africa: a systematic scoping review of practices and recommendations.Tropical medicine and health · 2026Article
- Review
- Effect of prenatal alcohol consumption on maternal anemia among pregnant women in Gondar town, Northwest Ethiopia: a retrospective cohort study.International health · 2025Article
- Prevalence and risk factors of intestinal parasitic infections in pregnancy: a cross-sectional study in a rural district in Ghana.BMC pregnancy and childbirth · 2025Article
- Prevalence and risk factors of anemia in internationally adopted children: a cohort study.Italian journal of pediatrics · 2025Article
- Epidemiological feature of imported malaria in Taiwan during the 2014-to-2020 period.Medicine · 2025Article
- Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China.Scientific reports · 2025Observational
- Malaria and Soil-Transmitted Helminth Co-Infection and Its Association With Anemia Among Pregnant Women Visiting Mizan-Tepi University Teaching Hospital, Southwest Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Iron Deficiency Anemia and Associated Factors During Pregnancy: A Longitudinal Study of Women Attending Antenatal Care Facility in Nigeria.Journal of chiropractic medicine · 2025Article
- Routine uptake of prenatal iron-folic acid supplementation and associated factors among pregnant women in peri-urban areas of Dodoma City, Tanzania: a cross-sectional study.BMC pregnancy and childbirth · 2024Article
- Prevalence and associated factors of schistosomiasis among pregnant women in northern Senegal.BMC infectious diseases · 2024Article
- Geographic inequalities and determinants of anaemia among preeclamptic women: a cross-sectional sample-based study in Bangladesh.BMC public health · 2024Article
- Prevalence of Soil-Transmitted Helminth Infections and Associated Risk Factors Among School Children in Dembecha Town, Ethiopia.Environmental health insights · 2024Article
- Adapting the preterm birth phenotyping framework to a low-resource, rural setting and applying it to births from Migori County in western Kenya.BMC pregnancy and childbirth · 2023Observational
- Malaria, Urogenital Schistosomiasis, and Anaemia in Pregnant Ghanaian Women.Journal of parasitology research · 2023Article
- The Global Prevalence ofTropical medicine and infectious disease · 2022Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundRelative contribution of these infections on anemia in pregnancy is not certain. While measures to protect pregnant women against malaria have been scaling up, interventions against helminthes have received much less attention. In this study, we determine the relative impact of helminthes and malaria on maternal anemia.
methodsA prospective observational study was conducted in coastal Kenya among a cohort of pregnant women who were recruited at their first antenatal care (ANC) visit and tested for malaria, hookworm, and other parasitic infections and anemia at enrollment. All women enrolled in the study received presumptive treatment with sulfadoxine-pyrimethamine, iron and multi-vitamins and women diagnosed with helminthic infections were treated with albendazole. Women delivering a live, term birth, were also tested for maternal anemia, fetal anemia and presence of infection at delivery. PRINCIPAL
findingsOf the 706 women studied, at the first ANC visit, 27% had moderate/severe anemia and 71% of women were anemic overall. The infections with highest prevalence were hookworm (24%), urogenital schistosomiasis (17%), trichuria (10%), and malaria (9%). In adjusted and unadjusted analyses, moderate/severe anemia at first ANC visit was associated with the higher intensities of hookworm and P. falciparum microscopy-malaria infections. At delivery, 34% of women had moderate/severe anemia and 18% of infants' cord hemoglobin was consistent with fetal anemia. While none of the maternal infections were significantly associated with fetal anemia, moderate/severe maternal anemia was associated with fetal anemia.
conclusionsMore than one quarter of women receiving standard ANC with IPTp for malaria had moderate/severe anemia in pregnancy and high rates of parasitic infection. Thus, addressing the role of co-infections, such as hookworm, as well as under-nutrition, and their contribution to anemia is needed.
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