ArticlePloS one2014
Population-based incidence of severe acute respiratory virus infections among children aged <5 years in rural Bangladesh, June-October 2010.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Hospital utilization rates for influenza and RSV: a novel approach and critical assessment.Population health metrics · 2021Pooled it
- Respiratory syncytial virus hospitalization and mortality: Systematic review and meta-analysis.Pediatric pulmonology · 2017Pooled it
- Antibiotics for preventing lower respiratory tract infections in high-risk children aged 12 years and under.The Cochrane database of systematic reviews · 2015Pooled it
- Maternal vitamin D supplementation during pregnancy and lactation to prevent acute respiratory infections in infancy in Dhaka, Bangladesh (MDARI trial): protocol for a prospective cohort study nested within a randomized controlled trial.BMC pregnancy and childbirth · 2016Trial
- Perceived Causes of Illness Among Infants and Young Children in Bangladesh: An Exploratory Qualitative Study.Healthcare (Basel, Switzerland) · 2025Article
- Moving beyond Wastewater: Perspectives on Environmental Surveillance of Infectious Diseases for Public Health Action in Low-Resource Settings.Environment & health (Washington, D.C.) · 2024Article
- Predictors of Respiratory Syncytial Virus, Influenza Virus, and Human Metapneumovirus Carriage in Children Under 5 Years With WHO-Defined Fast-Breathing Pneumonia in Pakistan.Influenza and other respiratory viruses · 2024Article
- Respiratory Syncytial Virus-Associated Deaths among Children under Five before and during the COVID-19 Pandemic in Bangladesh.Viruses · 2024Article
- Urban-rural difference in factors associated with childhood functional difficulty in Bangladesh: a cross-sectional study.Frontiers in public health · 2023Article
- Pre COVID-19 molecular epidemiology of respiratory syncytial virus (RSV) among children in Bangladesh.Heliyon · 2022Article
- Incidence of respiratory virus illness and hospitalizations in a Panama and El Salvador birth cohort, 2014-2018.Lancet regional health. Americas · 2022Article
- Respiratory syncytial virus-associated hospitalisation in children aged ≤5 years: a scoping review of literature from 2009 to 2021.ERJ open research · 2022Article
- Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia.BMC pediatrics · 2022Article
- Early Changes in Interferon Gene Expression and Antibody Responses Following Influenza Vaccination in Pregnant Women.The Journal of infectious diseases · 2022Article
- Incidence and seasonality of respiratory viruses among medically attended children with acute respiratory infections in an Ecuador birth cohort, 2011-2014.Influenza and other respiratory viruses · 2022Article
- Epidemiology and seasonality of human parainfluenza serotypes 1-3 in Australian children.Influenza and other respiratory viruses · 2021Article
- Article
- Burden of Acute Respiratory Infections Among Under-Five Children in Relation to Household Wealth and Socioeconomic Status in Bangladesh.Tropical medicine and infectious disease · 2019Article
- Determining the Cause of Death Among Children Hospitalized With Respiratory Illness in Kenya: Protocol for Pediatric Respiratory Etiology Surveillance Study (PRESS).JMIR research protocols · 2019Article
- Changes in inequality of childhood morbidity in Bangladesh 1993-2014: A decomposition analysis.PloS one · 2019Article
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Authors and funding
17 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundBetter understanding the etiology-specific incidence of severe acute respiratory infections (SARIs) in resource-poor, rural settings will help further develop and prioritize prevention strategies. To address this gap in knowledge, we conducted a longitudinal study to estimate the incidence of SARIs among children in rural Bangladesh.
methodsDuring June through October 2010, we followed children aged <5 years in 67 villages to identify those with cough, difficulty breathing, age-specific tachypnea and/or danger signs in the community or admitted to the local hospital. A study physician collected clinical information and obtained nasopharyngeal swabs from all SARI cases and blood for bacterial culture from those hospitalized. We tested swabs for respiratory syncytial virus (RSV), influenza viruses, human metapneumoviruses, adenoviruses and human parainfluenza viruses 1-3 (HPIV) by real-time reverse transcription polymerase chain reaction. We calculated virus-specific SARI incidence by dividing the number of new illnesses by the person-time each child contributed to the study.
resultsWe followed 12,850 children for 279,029 person-weeks (pw) and identified 141 SARI cases; 76 (54%) at their homes and 65 (46%) at the hospital. RSV was associated with 7.9 SARI hospitalizations per 100,000 pw, HPIV3 2.2 hospitalizations/100,000 pw, and influenza 1.1 hospitalizations/100,000 pw. Among non-hospitalized SARI cases, RSV was associated with 10.8 illnesses/100,000 pw, HPIV3 1.8/100,000 pw, influenza 1.4/100,000 pw, and adenoviruses 0.4/100,000 pw.
conclusionRespiratory viruses, particularly RSV, were commonly associated with SARI among children. It may be useful to explore the value of investing in prevention strategies, such as handwashing and respiratory hygiene, to reduce respiratory infections among young children in such settings.
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