Evidence map›Paper›PMID 24587152›Full record

SynthesisPloS one2014

Disparities and risks of sexually transmissible infections among men who have sex with men in China: a meta-analysis and data synthesis.

Eric P F Chow, Joseph D Tucker, Frank Y Wong, Eric J Nehl, Yanjie Wang, Xun Zhuang, Lei Zhang

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Eric P F ChowThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia ; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia ; Melbourne Sexual Health Centre, Alfred Hospital, Melbourne, VIC, Australia ; Comprehensive AIDS Research Center, School of Medicine, Tsinghua University, Beijing, China.
Joseph D TuckerUniversity of North Carolina Project-China, Guangzhou, China ; London School of Hygiene and Tropical Medicine, London, United Kingdom.
Frank Y WongDepartment of Behavioral Sciences and Health Education, Emory University, Atlanta, Georgia, United States of America.
Eric J NehlDepartment of Behavioral Sciences and Health Education, Emory University, Atlanta, Georgia, United States of America.
Yanjie WangThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Xun ZhuangSchool of Public Health, Nantong University, Nantong, Jiangsu Province, China.
Lei ZhangThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia ; Comprehensive AIDS Research Center, School of Medicine, Tsinghua University, Beijing, China.
Emory University · USUNSW Sydney · AULondon School of Hygiene & Tropical Medicine · GBNantong University · CNTsinghua University · CN

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs), including Hepatitis B and C virus, are emerging public health risks in China, especially among men who have sex with men (MSM). This study aims to assess the magnitude and risks of STIs among Chinese MSM.

methodsChinese and English peer-reviewed articles were searched in five electronic databases from January 2000 to February 2013. Pooled prevalence estimates for each STI infection were calculated using meta-analysis. Infection risks of STIs in MSM, HIV-positive MSM and male sex workers (MSW) were obtained. This review followed the PRISMA guidelines and was registered in PROSPERO.

resultsEighty-eight articles (11 in English and 77 in Chinese) investigating 35,203 MSM in 28 provinces were included in this review. The prevalence levels of STIs among MSM were 6.3% (95% CI: 3.5-11.0%) for chlamydia, 1.5% (0.7-2.9%) for genital wart, 1.9% (1.3-2.7%) for gonorrhoea, 8.9% (7.8-10.2%) for hepatitis B (HBV), 1.2% (1.0-1.6%) for hepatitis C (HCV), 66.3% (57.4-74.1%) for human papillomavirus (HPV), 10.6% (6.2-17.6%) for herpes simplex virus (HSV-2) and 4.3% (3.2-5.8%) for Ureaplasma urealyticum. HIV-positive MSM have consistently higher odds of all these infections than the broader MSM population. As a subgroup of MSM, MSW were 2.5 (1.4-4.7), 5.7 (2.7-12.3), and 2.2 (1.4-3.7) times more likely to be infected with chlamydia, gonorrhoea and HCV than the broader MSM population, respectively.

conclusionPrevalence levels of STIs among MSW were significantly higher than the broader MSM population. Co-infection of HIV and STIs were prevalent among Chinese MSM. Integration of HIV and STIs healthcare and surveillance systems is essential in providing effective HIV/STIs preventive measures and treatments.

trial registrationPROSPERO NO: CRD42013003721.

Indexed as

ChinaCoinfectionHIV InfectionsHomosexuality, MaleHumansMaleOdds RatioPrevalenceRisk AssessmentSexually Transmitted DiseasesSex Workers

Identifiers

PMID24587152
PMCPMC3933676
OpenAlexW2061101294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.