ArticlePloS one2014
Analysis of differential gene expression and novel transcript units of ovine muscle transcriptomes.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- LNC_003296 regulates the proliferation and differentiation of ovine myoblasts by modulating the stability of Hsp70.The veterinary quarterly · 2026Article
- Integrated LC-MS-based lipidomics and transcriptomics reveal lipid heterogeneity and flavour variation in different cuts of muscles from Sadumont lamb.Food chemistry. Molecular sciences · 2026Article
- Integrated transcriptomics and metabolomics reveal the molecular characteristics and metabolic regulatory mechanisms among different muscles in Minxian black fur sheep.BMC genomics · 2025Article
- Transcriptome analysis revealed the mechanism of skeletal muscle growth and development in different hybrid sheep.Animal bioscience · 2025Article
- Epigenetic landscape revealsFrontiers in nutrition · 2025Article
- Dynamic mRNA network profiles in macrophages challenged with lipopolysaccharide.American journal of translational research · 2024Article
- Gene Structure, Expression and Function Analysis ofInternational journal of molecular sciences · 2023Article
- Identification of Genes Related to Squab Muscle Growth and Lipid Metabolism from Transcriptome Profiles of Breast Muscle and Liver in Domestic Pigeon (Animals : an open access journal from MDPI · 2022Article
- Transcriptome Analysis of the Liver and Muscle Tissues of Dorper and Small-Tailed Han Sheep.Frontiers in genetics · 2022Article
- Analysis of reproduction-related transcriptomes on pineal-hypothalamic-pituitary-ovarian tissues during estrus and anestrus in Tan sheep.Frontiers in veterinary science · 2022Article
- Screening of Genes Related to Growth, Development and Meat Quality of Sahan Crossbred F1 Sheep Based on RNA-Seq Technology.Frontiers in veterinary science · 2022Article
- Excavation of Genes Related to the Mining of Growth, Development, and Meat Quality of Two Crossbred Sheep Populations Based on Comparative Transcriptomes.Animals : an open access journal from MDPI · 2021Article
- Comparative Transcriptome Analysis of Milk Somatic Cells During Lactation Between Two Intensively Reared Dairy Sheep Breeds.Frontiers in genetics · 2021Article
- Article
- Longissimus Dorsi Muscle Transcriptomic Analysis of Simmental and Chinese Native Cattle Differing in Meat Quality.Frontiers in veterinary science · 2020Article
- Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect.Open medicine (Warsaw, Poland) · 2019Article
- Hepatic metabolomics and transcriptomics to study susceptibility to ketosis in response to prepartal nutritional management.Journal of animal science and biotechnology · 2019Article
- Article
- The Effects of Radix Astragali Water Abstract on Energy Metabolism in Rat Yang-Deficiency Cold Syndrome Model through PPAR Signaling Pathway.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we characterized differentially expressed genes (DEGs) between the muscle transcriptomes of Small-tailed Han sheep and Dorper sheep and predicted novel transcript units using high-throughput RNA sequencing technology. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses showed that 1,300 DEGs were involved in cellular processes, metabolic pathways, and the actin cytoskeleton pathway. Importantly, we identified 34 DEGs related to muscle cell development and differentiation. Additionally, we were able to optimize the gene structure and predict the untranslated regions (UTRs) for some of the DEGs. Among the 123,678 novel predicted transcript units (TUs), 15,015 units were predicted protein sequences. The reliability of the sequencing data was verified through qRT-PCR analysis of 12 genes. These results will provide useful information for functional genetic research in the future.
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