ReviewPloS one2014
Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review.
Review in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Antineutrophil cytoplasmic antibodies in infective endocarditis: a case report and systematic review of the literature.Clinical rheumatology · 2022Pooled it
- Infective Endocarditis-Associated Glomerulonephritis Caused byKidney & blood pressure research · 2026Article
- Infective endocarditis mimicking antineutrophil-cytoplasmic-antibody-associated vasculitis with glomerulonephritis: a case report.Journal of medical case reports · 2025Article
- Abiotrophia defectiva endocarditis implicated in antineutrophil cytoplasmic antibody-negative glomerulonephritis.BMJ case reports · 2025Article
- Proteinase‑3‑antineutrophil cytoplasmic antibody‑associated vasculitis secondary to subacute infective endocarditis: A case report.Experimental and therapeutic medicine · 2024Article
- Bartonella henselae infection-mediated shunt nephritis.Clinical nephrology. Case studies · 2024Article
- Novel putative biomarkers for infective endocarditis by serum proteomic analysis: a comprehensive review of literature.Annals of medicine and surgery (2012) · 2023Article
- Diagnostic Work-Up in Patients with Nonbacterial Thrombotic Endocarditis.Journal of clinical medicine · 2023Review
- Clinicopathological differences between Bartonella and other bacterial endocarditis-related glomerulonephritis - our experience and a pooled analysis.Frontiers in nephrology · 2023Review
- Endocarditis-associated rapidly progressive glomerulonephritis mimicking vasculitis: a diagnostic and treatment challenge.Annals of medicine · 2022Article
- The clinical pattern differentiates ANCA-positive infective endocarditis patients from ANCA-associated vasculitis patients: a 23 years' retrospective cohort study in China and follow-ups.Clinical rheumatology · 2022Article
- ANCA-associated vasculitis with cardiac valve vegetations in two teenage males: two case reports and a literature review.Pediatric rheumatology online journal · 2022Review
- Infective Endocarditis-Associated Pauci-Immune Glomerulonephritis in a Patient With Cryoglobulinemia.Cureus · 2022Article
- Infective Endocarditis-Associated Glomerulonephritis: A Comprehensive Review of the Clinical Presentation, Histopathology, and Management.Yonago acta medica · 2022Review
- Babesiosis and the human immune system.IDCases · 2022Article
- Factors Affecting the Progression of Infection-Related Glomerulonephritis to Chronic Kidney Disease.International journal of molecular sciences · 2021Review
- ANCA-associated vasculitis.Nature reviews. Disease primers · 2020Review
- Antineutrophil cytoplasmic antibodies (ANCA)-positive patient with infective endocarditis and chronic hepatitis B virus: a case report and review of the literature.Journal of medical case reports · 2020Review
- Article
- Double-Valve Heart Disease and Glomerulonephritis Consequent to Abiotrophia defectiva Endocarditis.Texas Heart Institute journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveChronic infections tend to induce the production of antineutrophil cytoplasmic antibody (ANCA). Infective endocarditis (IE) has been reported to exhibit positive ANCA tests and to mimic ANCA-associated vasculitis, which may lead to a misdiagnosis and inappropriate treatment. The aim of this study was to clarify whether there is any difference in the clinical features between ANCA-positive IE and ANCA-negative IE.
methodsA retrospective study was carried out on 39 IE patients whose proteinase 3 (PR3)-ANCA and myeloperoxidase (MPO)-ANCA levels were measured. After dividing the patients into ANCA-positive and ANCA-negative IE, we compared their clinical features.
resultswe compared 13 ANCA-positive IE patients with 26 ANCA-negative IE patients. All 13 ANCA-positive IE patients were proteinase-3-ANCA positive. Compared with the ANCA-negative IE group, the prevalence of edema of the lower extremities, the serum lactate dehydrogenase (LDH) level and positive blood cultures rate were higher in ANCA-positive IE group, but there was no significant difference in other clinical features.
conclusionTherefore, if a patient presents with fever, arthralgia, skin rash and is ANCA-positive, appropriate steps should be taken to exclude infection (especially IE) before confirming the diagnosis of ANCA-associated vasculitis and embarking on long-term immunosuppressive therapy.
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