ArticlePloS one2014
Genome re-sequencing and functional analysis places the Phytophthora sojae avirulence genes Avr1c and Avr1a in a tandem repeat at a single locus.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- A global-temporal analysis on Phytophthora sojae resistance-gene efficacy.Nature communications · 2023Pooled it
- A Rare Recombination in the Phytophthora sojae Genome Allows the Redefinition of a Major Avirulence Gene.Molecular plant pathology · 2026Article
- Epigenetic modulation of fungal pathogens: a focus onFrontiers in microbiology · 2024Review
- Mitochondrial Inner Membrane ABC Transporter Bcmdl1 Is Involved in Conidial Germination, Virulence, and Resistance to Anilinopyrimidine Fungicides in Botrytis cinerea.Microbiology spectrum · 2023Article
- Progress and Challenges in Elucidating the Functional Role of Effectors in the Soybean-Journal of fungi (Basel, Switzerland) · 2022Review
- RXLR effector gene Avr3a from Phytophthora sojae is recognized by Rps8 in soybean.Molecular plant pathology · 2022Article
- Epigenetics of wheat-rust interaction: an update.Planta · 2022Review
- Molecular mechanisms ofFrontiers in microbiology · 2022Review
- Mutations in the Promoter and Coding Regions ofFrontiers in microbiology · 2021Article
- Whole Genome Re-sequencing Reveals Natural Variation and Adaptive Evolution ofFrontiers in microbiology · 2019Article
- Stable predictive markers for Phytophthora sojae avirulence genes that impair infection of soybean uncovered by whole genome sequencing of 31 isolates.BMC biology · 2018Article
- Gene expression polymorphism underpins evasion of host immunity in an asexual lineage of the Irish potato famine pathogen.BMC evolutionary biology · 2018Article
- A Novel Phytophthora sojae Resistance Rps12 Gene Mapped to a Genomic Region That Contains Several Rps Genes.PloS one · 2017Article
- Escaping Host Immunity: New Tricks for Plant Pathogens.PLoS pathogens · 2016Review
- Article
- Epigenetic control of effectors in plant pathogens.Frontiers in plant science · 2014Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this work was to map and identify the Phytophthora sojae Avr1c gene. Progeny from a cross of P. sojae strains ACR10×P7076 were tested for virulence on plants carrying Rps1c. Results indicate that avirulence segregates as a dominant trait. We mapped the Avr1c locus by performing whole genome re-sequencing of composite libraries created from pooled samples. Sequence reads from avirulent (Pool1) and virulent (Pool2) samples were aligned to the reference genome and single nucleotide polymorphisms (SNP) were identified for each pool. High quality SNPs were filtered to select for positions where SNP frequency was close to expected values for each pool. Only three SNP positions fit all requirements, and these occurred in close proximity. Additional DNA markers were developed and scored in the F₂ progeny, producing a fine genetic map that places Avr1c within the Avr1a gene cluster. Transient expression of Avr1c or Avr1a triggers cell death on Rps1c plants, but Avr1c does not trigger cell death on Rps1a plants. Sequence comparisons show that the RXLR effector genes Avr1c and Avr1a are closely related paralogs. Gain of virulence on Rps1c in P. sojae strain P7076 is achieved by gene deletion, but in most other strains this is accomplished by gene silencing. This work provides practical tools for crop breeding and diagnostics, as the Rps1c gene is widely deployed in commercial soybean cultivars.
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