Evidence map›Paper›PMID 24586478›Full record

SynthesisPloS one2014

Non-adherence in patients on peritoneal dialysis: a systematic review.

Konstadina Griva, Alden Yuanhong Lai, Haikel Asyraf Lim, Zhenli Yu, Marjorie Wai Yin Foo, Stanton P Newman

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Konstadina GrivaDepartment of Psychology, National University of Singapore, Singapore ; Unit of Behavioural Medicine, University College London, London, United Kingdom.
Alden Yuanhong LaiDepartment of Psychology, National University of Singapore, Singapore.
Haikel Asyraf LimDepartment of Psychology, National University of Singapore, Singapore.
Zhenli YuDepartment of Renal Medicine, Khoo Teck Puat Hospital, Singapore.
Marjorie Wai Yin FooDepartment of Nephrology, Peritoneal Dialysis Centre, Singapore General Hospital, Singapore.
Stanton P NewmanUnit of Behavioural Medicine, University College London, London, United Kingdom ; Health Services Research Group, City University London, London, United Kingdom.
National University of Singapore · SGCity, University of London · GBKhoo Teck Puat Hospital · SGSingapore General Hospital · SGUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been increasingly recognized that non-adherence is an important factor that determines the outcome of peritoneal dialysis (PD) therapy. There is therefore a need to establish the levels of non-adherence to different aspects of the PD regimen (dialysis procedures, medications, and dietary/fluid restrictions).

methodsA systematic review of peer-reviewed literature was performed in PubMed, PsycINFO and CINAHL databases using PRISMA guidelines in May 2013. Publications on non-adherence in PD were selected by two reviewers independently according to predefined inclusion and exclusion criteria. Relevant data on patient characteristics, measures, rates and factors associated with non-adherence were extracted. The quality of studies was also evaluated independently by two reviewers according to a revised version of the Effective Public Health Practice Project assessment tool.

resultsThe search retrieved 204 studies, of which a total of 25 studies met inclusion criteria. Reported rates of non-adherence varied across studies: 2.6-53% for dialysis exchanges, 3.9-85% for medication, and 14.4-67% for diet/fluid restrictions. Methodological differences in measurement and definition of non-adherence underlie the observed variation. Factors associated with non-adherence that showed a degree of consistency were mostly socio-demographical, such as age, employment status, ethnicity, sex, and time period on PD treatment.

conclusionNon-adherence to different dimensions of the dialysis regimen appears to be prevalent in PD patients. There is a need for further, high-quality research to explore these factors in more detail, with the aim of informing intervention designs to facilitate adherence in this patient population.

Indexed as

Medication AdherencePatient CompliancePeritoneal DialysisAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedProspective StudiesRetrospective Studies

Identifiers

PMID24586478
PMCPMC3934877
OpenAlexW2074832593

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.