ArticlePloS one2014
Estimating colorectal cancer treatment costs: a pragmatic approach exemplified by health insurance data from Germany.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prevalence and determinants of financial toxicity in patients with colorectal cancer: a systematic review and meta-analysis.International journal for equity in health · 2026Pooled it
- Economic Burden of Pancreatic Cancer in Europe: a Literature Review.Journal of gastrointestinal cancer · 2023Pooled it
- Lifetime direct healthcare costs of treating colorectal cancer: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Pooled it
- An evidence mapping of systematic reviews and meta-analysis on traditional Chinese medicine for ulcerative colitis.BMC complementary medicine and therapies · 2021Pooled it
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- Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention.The international journal of behavioral nutrition and physical activity · 2020Trial
- Medical treatment cost for Chinese inpatients with colorectal cancer by sites.Frontiers in public health · 2025Observational
- Explorative cost-effectiveness analysis of colorectal cancer recurrence detection with next-generation sequencing liquid biopsy in Spain, France, and Germany.Therapeutic advances in gastroenterology · 2024Article
- Impact of Reducing Intake of Red and Processed Meat on Colorectal Cancer Incidence in Germany 2020 to 2050-A Simulation Study.Nutrients · 2023Article
- Added value of quantitative, multiparametric 18F-FDG PET/MRI in the locoregional staging of rectal cancer.European journal of nuclear medicine and molecular imaging · 2022Article
- Treatment Costs of Colorectal Cancer by Sex and Age: Population-Based Study on Health Insurance Data from Germany.Cancers · 2022Article
- Resource Use and Costs Associated to the Initial Phase of Treatment for Patients with Colorectal Cancer Receiving Post-Surgery Chemotherapy: A Cost Analysis from a Healthcare Perspective.Iranian journal of public health · 2021Article
- Article
- Till death do us part: the effect of marital status on health care utilization and costs at end-of-life. A register study on all colorectal cancer decedents in Norway between 2009 and 2013.BMC health services research · 2020Article
- Cost-utility of colorectal cancer screening at 40 years old for average-risk patients.Preventive medicine · 2020Article
- A Correlation Study of the Colorectal Cancer Statistics and Economic Indicators in Selected Balkan Countries.Frontiers in public health · 2020Article
- Management and intensity of medical end-of-life care in people with colorectal cancer during the year before their death in 2015: A French national observational study.Cancer medicine · 2019Observational
- Novel cancer chemotherapy hits by molecular topology: dual Akt and Beta-catenin inhibitors.PloS one · 2015Article
- Variation in treatment modalities, costs and outcomes of rectal cancer patients in Poland.Contemporary oncology (Poznan, Poland) · 2015Article
- Cost trend analysis of initial cancer treatment in Taiwan.PloS one · 2014Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe cost of colorectal cancer (CRC) treatment is a crucial parameter to inform cost-effectiveness analyses on CRC screening but it is not readily available and therefore often lacking. We aimed to elaborate and exemplify a pragmatic approach to estimate CRC treatment cost based on health insurance data from Germany.
methodsWe included two groups of persons who were continuously health-insured between 2005-2010: A) Cases: Persons with a hospital discharge diagnosis of CRC (ICD C18-C20) between 2007-2010 and no such a diagnosis between 2005-2006 (to focus on incident CRC cases); B) Controls: Persons without a diagnosis of CRC during the observation period, matched to CRC cases by age and sex (matching factor: 1∶5). We considered in-patient, out-patient and drug costs and calculated incremental costs as the difference in means between cases and controls. We divided costs into three phases of care (initial, intermediate and end-of-life phase).
resultsThe initial, the intermediate and the end-of-life phase included 12,792, 5,280, and 3,779 CRC cases, respectively, and 63,960, 26,400, and 18,895 controls. The mean incremental costs--annualized for each phase--were €26,000, €2,300, and €51,700, respectively. The costs of the initial phase of care were higher for rectal than for colon cancer. Annualized stage-specific cost estimates ranged from €15,000 to €21,300 for early stages and from €29,800 to €35,000 for late stages.
conclusionThis pragmatic and feasible approach provided plausible estimates of CRC treatment costs in Germany; being transferable to other settings, it may thus facilitate to weigh up potential savings in treatment costs against the resources required for CRC control programs in various countries.
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