ArticlePloS one2014
Polyphasic analysis of a middle ages coprolite microbiota, Belgium.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Targeted pathogen profiling of ancient feces reveals common enteric infections in the Rio Zape Valley, 725-920 CE.PloS one · 2025Article
- Microbiome characterization of a pre-Hispanic man from Zimapán, Mexico: Insights into ancient gut microbial communities.PloS one · 2025Article
- Innovations in MALDI-TOF Mass Spectrometry: Bridging modern diagnostics and historical insights.Open life sciences · 2025Review
- Stalactites Core Prospect as Environmental "Microbial Ark": The Actinomycetota Diversity Paradigm, First Reported from a Greek Cave.Polish journal of microbiology · 2023Article
- Geographically diverse canid sampling provides novel insights into pre-industrial microbiomes.Proceedings. Biological sciences · 2022Article
- The puzzle of the evolutionary natural history of tuberculosis.New microbes and new infections · 2021Review
- Intestinal helminths as a biomolecular complex in archaeological research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Functional diversity of microbial ecologies estimated from ancient human coprolites and dental calculus.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- A comparative study of parasites in three latrines from Medieval and Renaissance Brussels, Belgium (14th-17th centuries).Parasitology · 2020Article
- Metagenomics and microscope revealed T. trichiura and other intestinal parasites in a cesspit of an Italian nineteenth century aristocratic palace.Scientific reports · 2020Article
- Five millennia of Bartonella quintana bacteraemia.PloS one · 2020Article
- Urinary shedding of pathogenic Leptospira in stray dogs and cats, Algiers: A prospective study.PloS one · 2018Article
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- Paleoproteomics of the Dental Pulp: The plague paradigm.PloS one · 2017Article
- Insights into human evolution from ancient and contemporary microbiome studies.Current opinion in genetics & development · 2016Review
- Paleomicrobiology: a Snapshot of Ancient Microbes and Approaches to Forensic Microbiology.Microbiology spectrum · 2016Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paleomicrobiological investigations of a 14(th)-century coprolite found inside a barrel in Namur, Belgium were done using microscopy, a culture-dependent approach and metagenomics. Results were confirmed by ad hoc PCR--sequencing. Investigations yielded evidence for flora from ancient environment preserved inside the coprolite, indicated by microscopic observation of amoebal cysts, plant fibers, seeds, pollens and mold remains. Seventeen different bacterial species were cultured from the coprolite, mixing organisms known to originate from the environment and organisms known to be gut inhabitants. Metagenomic analyses yielded 107,470 reads, of which known sequences (31.9%) comprised 98.98% bacterial, 0.52% eukaryotic, 0.44% archaeal and 0.06% viral assigned reads. Most abundant bacterial phyla were Proteobacteria, Gemmatimonadetes, Actinobacteria and Bacteroidetes. The 16 S rRNA gene dataset yielded 132,000 trimmed reads and 673 Operational Taxonomic Units. Most abundant bacterial phyla observed in the 16 S rRNA gene dataset belonged to Proteobacteria, Firmicutes, Actinobacteria and Chlamydia. The Namur coprolite yielded typical gut microbiota inhabitants, intestinal parasites Trichuris and Ascaris and systemic pathogens Bartonella and Bordetella. This study adds knowledge to gut microbiota in medieval times.
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