Evidence map›Paper›PMID 24585567›Full record

GuidelineClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014

Prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: Updated Guidelines from the Centers for Disease Control and Prevention, National Institutes of Health, and HIV Medicine Association of the Infectious Diseases Society of America.

Henry Masur, John T Brooks, Constance A Benson, King K Holmes, Alice K Pau, Jonathan E Kaplan, National Institutes of Health, Centers for Disease Control and Prevention, HIV Medicine Association of the Infectious Diseases Society of America

2 registry-linked trialsOpen access · hybridAbstract readGuideline
In one paragraph

Guideline in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 127 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 7 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03092817 phase3completednot on this mapstarted 2017, after this paper: background citation

A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis

TypeinterventionalSponsorOxford University Clinical Research Unit, VietnamRan2017 to 2023Enrolled520ConditionsTuberculosis, Tuberculous Meningitis, Drug-Induced Liver Injury, HIVArmsDexamethasone, Placebo
NCT03100786 phase3completednot on this mapstarted 2018, after this paper: background citation

A Randomized Double Blind Placebo Controlled Non-inferiority Trial of Adjunctive Dexamethasone for the Treatment of HIV-uninfected Adults With Tuberculous Meningitis Stratified by Leukotriene A4 Hydrolase Genotype

TypeinterventionalSponsorOxford University Clinical Research Unit, VietnamRan2018 to 2024Enrolled702ConditionsTuberculosis, Tuberculous Meningitis, Drug-Induced Liver InjuryArmsDexamethasone, Placebo
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 7 syntheses or guidelines pooled it, 262 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2019
    Guideline
  5. Pooled it
  6. Guideline
  7. Guideline
  8. Trial
  9. Hepatitis B Vaccination Induced TNF-Journal of immunology research · 2018
    Trial
  10. Are CD4Livers · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Henry MasurNational Institutes of Health, Bethesda, Maryland.
John T Brooks
Constance A Benson
King K Holmes
Alice K Pau
Jonathan E Kaplan
National Institutes of Health
Centers for Disease Control and Prevention
HIV Medicine Association of the Infectious Diseases Society of America
Centers for Disease Control and Prevention · USNational Institutes of Health · USUniversity of California, San Diego · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In May 2013, a revised and updated version of the Centers for Disease Control and Prevention/National Institutes of Health/HIV Medicine Association Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents was released online. These guidelines, since their inception in 1989, have been widely accessed in the United States and abroad. These guidelines have focused on the management of HIV/AIDS-related opportunistic infections that occur in the United States. In other parts of the world, the spectrum of complications may be different and the resources available for diagnosis and management may not be identical to those in the United States. The sections that have been most extensively updated are those on immune reconstitution inflammatory syndrome, tuberculosis, hepatitis B, hepatitis C, human papillomavirus, and immunizations. The guidelines will not be published in hard copy form. This document will be revised as needed throughout each year as new data become available.

Indexed as

AdolescentAdultAIDS-Related Opportunistic InfectionsCenters for Disease Control and Prevention, U.S.Hepatitis BHepatitis CHIV InfectionsHumansImmune Reconstitution Inflammatory SyndromeNational Institutes of Health (U.S.)Papillomavirus InfectionsTuberculosisUnited StatesguidelineHIV/AIDSonlineopportunistic infectionsrevision

Identifiers

PMID24585567
PMCPMC3982842
OpenAlexW2114940577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.