ArticleHuman brain mapping2014
Efficiency of weak brain connections support general cognitive functioning.
Article in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
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Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large-scale resting-state functional brain networks in aging.Psychophysiology · 2023Pooled it
- Trial
- Intelligence and eeg measures of information flow: efficiency and homeostatic neuroplasticity.Scientific reports · 2016Trial
- The network architecture of general intelligence in the human connectome.Nature communications · 2026Article
- Odor-induced sweetness enhancement: EEG evidence for olfactory and gustatory cross-modal interactions.Current research in food science · 2026Article
- Functional network organization is locally atypical in children, adolescents, and young adults with congenital heart disease.NeuroImage. Clinical · 2026Article
- Altered resting-state prefrontal activity and network topology in adolescents with depression: an fNIRS study.Frontiers in psychiatry · 2026Article
- Introduction to correlation networks: Interdisciplinary approaches beyond thresholding.Physics reports · 2025Article
- Somatomotor Disconnection Links Sleep Duration With Socioeconomic Context, Screen Time, Cognition, and Psychopathology.Biological psychiatry global open science · 2025Article
- Regional, but not brain-wide, graph theoretic measures are robustly and reproducibly linked to general cognitive ability.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The multiscale self-similarity of the weighted human brain connectome.PLoS computational biology · 2025Article
- Manatee cognition and behavior: a neurobiological perspective on an unusual constellation of senses and a unique brain.Frontiers in behavioral neuroscience · 2025Article
- Presurgical structural connectivity predicts postsurgical cognitive impairment in glioma patients.Brain communications · 2025Article
- Improved whole-brain reconfiguration efficiency reveals mechanisms of speech rehabilitation in cleft lip and palate patients: an fMRI study.Frontiers in aging neuroscience · 2025Article
- Tell me why: A scoping review on the fundamental building blocks of fMRI-based network analysis.NeuroImage. Clinical · 2025Article
- Enhanced efficiency in the bilingual brain through the inter-hemispheric cortico-cerebellar pathway in early second language acquisition.Communications biology · 2024Article
- The Neural Correlates of Alcohol Approach Bias - New Insights from a Whole-Brain Network Analysis Perspective.medRxiv : the preprint server for health sciences · 2024Article
- Tai Chi Practice Buffers Aging Effects in Functional Brain Connectivity.Brain sciences · 2024Article
- Functional network modules overlap and are linked to interindividual connectome differences during human brain development.PLoS biology · 2024Article
- Task-specific topology of brain networks supporting working memory and inhibition.Human brain mapping · 2024Article
23 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain network topology provides valuable information on healthy and pathological brain functioning. Novel approaches for brain network analysis have shown an association between topological properties and cognitive functioning. Under the assumption that "stronger is better", the exploration of brain properties has generally focused on the connectivity patterns of the most strongly correlated regions, whereas the role of weaker brain connections has remained obscure for years. Here, we assessed whether the different strength of connections between brain regions may explain individual differences in intelligence. We analyzed-functional connectivity at rest in ninety-eight healthy individuals of different age, and correlated several connectivity measures with full scale, verbal, and performance Intelligent Quotients (IQs). Our results showed that the variance in IQ levels was mostly explained by the distributed communication efficiency of brain networks built using moderately weak, long-distance connections, with only a smaller contribution of stronger connections. The variability in individual IQs was associated with the global efficiency of a pool of regions in the prefrontal lobes, hippocampus, temporal pole, and postcentral gyrus. These findings challenge the traditional view of a prominent role of strong functional brain connections in brain topology, and highlight the importance of both strong and weak connections in determining the functional architecture responsible for human intelligence variability.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.