Is there cerebellar pathology in essential tremor?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Structural brain changes in the development of essential tremor: toward early diagnosis.Frontiers in aging neuroscience · 2026
   Article
2. Analysis of Fine Motor Skills in Essential Tremor: Combining Neuroimaging and Handwriting Biomarkers for Early Management.Frontiers in human neuroscience · 2021
   Article
3. Mapping Purkinje Cell Placement Along the Purkinje Cell Layer: an Analysis of Postmortem Tissue from Essential Tremor Patients vs. Controls.Cerebellum (London, England) · 2016
   Article
4. Essential Tremor: A Common Disorder of Purkinje Neurons?The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2016
   Review
5. Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis.Movement disorders : official journal of the Movement Disorder Society · 2016
   Article
6. Essential tremor is associated with disruption of functional connectivity in the ventral intermediate Nucleus--Motor Cortex--Cerebellum circuit.Human brain mapping · 2016
   Article
7. SCN4A pore mutation pathogenetically contributes to autosomal dominant essential tremor and may increase susceptibility to epilepsy.Human molecular genetics · 2015
   Article
8. The GABA Hypothesis in Essential Tremor: Lights and Shadows.Tremor and other hyperkinetic movements (New York, N.Y.) · 2014
   Article

Corrections and comments

• Comment on
  Essential tremor is not associated with cerebellar Purkinje cell loss.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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