ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2014
Evolutionary origin of higher-order repeat structure in alpha-satellite DNA of primate centromeres.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- The emergence and diversification of the DUX gene family across placental mammals.Communications biology · 2026Article
- Novel Cascade Alpha Satellite HORs in Orangutan Chromosome 13 Assembly: Discovery of the 59mer HOR-The largest Unit in Primates-And the Missing Triplet 45/27/18 HOR in Human T2T-CHM13v2.0 Assembly.International journal of molecular sciences · 2024Article
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- Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis.Nature communications · 2022Article
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- Sequence, Chromatin and Evolution of Satellite DNA.International journal of molecular sciences · 2021Review
- Review
- Satellite DNAs are conserved and differentially transcribed among Gryllus cricket species.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- New insights into the genome repetitive fraction of the Antarctic bivalve Adamussium colbecki.PloS one · 2018Article
- Regular Higher Order Repeat Structures in Beetle Tribolium castaneum Genome.Genome biology and evolution · 2017Article
- Satellite DNA: An Evolving Topic.Genes · 2017Review
- Lack of satellite DNA species-specific homogenization and relationship to chromosomal rearrangements in monitor lizards (Varanidae, Squamata).BMC evolutionary biology · 2017Article
- Identification and characterization of a subtelomeric satellite DNA in Callitrichini monkeys.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- High-throughput analysis of the satellitome revealed enormous diversity of satellite DNAs in the neo-Y chromosome of the cricket Eneoptera surinamensis.Scientific reports · 2017Article
- Formation of functional CENP-B boxes at diverse locations in repeat units of centromeric DNA in New World monkeys.Scientific reports · 2016Article
- CENP-B box, a nucleotide motif involved in centromere formation, occurs in a New World monkey.Biology letters · 2016Article
- Higher-order repeat structure in alpha satellite DNA occurs in New World monkeys and is not confined to hominoids.Scientific reports · 2015Article
- Reduction in the structural instability of cloned eukaryotic tandem-repeat DNA by low-temperature culturing of host bacteria.Genetics research · 2014Article
- Locational diversity of alpha satellite DNA and intergeneric hybridization aspects in the Nomascus and Hylobates genera of small apes.PloS one · 2014Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alpha-satellite DNA (AS) is a main DNA component of primate centromeres, consisting of tandemly repeated units of ~170 bp. The AS of humans contains sequences organized into higher-order repeat (HOR) structures, in which a block of multiple repeat units forms a larger repeat unit and the larger units are repeated tandemly. The presence of HOR in AS is widely thought to be unique to hominids (family Hominidae; humans and great apes). Recently, we have identified an HOR-containing AS in the siamang, which is a small ape species belonging to the genus Symphalangus in the family Hylobatidae. This result supports the view that HOR in AS is an attribute of hominoids (superfamily Hominoidea) rather than hominids. A single example is, however, not sufficient for discussion of the evolutionary origin of HOR-containing AS. In the present study, we developed an efficient method for detecting signs of large-scale HOR and demonstrated HOR of AS in all the three other genera. Thus, AS organized into HOR occurs widely in hominoids. Our results indicate that (i) HOR-containing AS was present in the last common ancestor of hominoids or (ii) HOR-containing AS emerged independently in most or all basal branches of hominoids. We have also confirmed HOR occurrence in centromeric AS in the Hylobatidae family, which remained unclear in our previous study because of the existence of AS in subtelomeric regions, in addition to centromeres, of siamang chromosomes.
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