ArticlePeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
Clinical outcome of home hemodialysis in patients with previous peritoneal dialysis exposure: evaluation of the integrated home dialysis model.
Article in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 27 citations in OpenAlex.
- Hospitalization Risk in the Integrated Home Dialysis Model: Analysis of the Canadian Organ Replacement Register.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Outcomes of Dialysis Modality Switch: A Matched Cohort Analysis from a National Renal Replacement Therapy Registry, 2010-2022.Journal of clinical medicine · 2026Article
- Personalized peritoneal dialysis prescription-beyond clinical or analytical values.Clinical kidney journal · 2024Article
- Integrated home dialysis model: facilitating home-to-home transition.Clinical kidney journal · 2024Article
- Peritoneal dialysis discontinuation: to the root of the problem.Journal of nephrology · 2023Review
- Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis.Kidney international reports · 2022Article
- Integrated care: enhancing transition from renal replacement therapy options to home haemodialysis.Clinical kidney journal · 2020Review
- Optimization of Dialysis Modality Transitions for Improved Patient Care.Canadian journal of kidney health and disease · 2019Review
- Home hemodialysis: a comprehensive review of patient-centered and economic considerations.ClinicoEconomics and outcomes research : CEOR · 2017Review
- Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisReview
- Integrated dialysis care-by chance or design?Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisArticle
- Predictors of Transfer to Home Hemodialysis after Peritoneal Dialysis Completion.Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisArticle
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHome dialysis is a cost-effective modality of renal replacement therapy associated with excellent outcomes. Peritoneal dialysis (PD) is the most common home-based modality, but technique failure remains a problem. Transfer from PD to home hemodialysis (HHD) allows the patient to continue with a home-based modality, but the outcomes of patients transitioning to HHD after PD are largely unknown.
methodsIn a retrospective cohort study, including all consecutive HHD patients between January 1996 and December 2011, we evaluated the outcomes of patients with previous PD exposure compared to those without. The primary outcome was the cumulative patient and technique survival. Secondary outcomes included time to first hospitalization and hospitalization rate. Data were compared using the log-rank test and a multivariable Cox proportional hazards model.
resultsAmong our cohort of 207 consecutive HHD patients, 35 (17%) had previous exposure to PD. Median renal replacement therapy (RRT) vintage (12.3 years, interquartile range (IQR) 8.5 - 18.9 vs 0.9 years, IQR 0.2 - 7.5, p < 0.001) and Charlson comorbidity index (CCI) (4, IQR 2 - 6 vs 3, IQR 2 - 4, p = 0.044) were higher among patients with PD exposure than those without. Despite the difference in vintage, cumulative patient and technique survival was similar in the two groups, in both unadjusted (log-rank p = 0.893) and Cox adjusted models (hazard ratio (HR) 1.15, 95% confidence interval (CI) 0.51 - 2.59) for patients with PD exposure compared to those without. The time to first hospitalization was shorter in patients with previous PD exposure compared to PD-naïve patients (log-rank p = 0.021). This association was preserved in the Cox proportional model (HR 1.65, 95% CI 1.08 - 2.54).
conclusionDespite a higher burden of comorbidity, patients with previous PD exposure had similar cumulative patient and technique survival on HHD compared to those without PD exposure. Whenever possible, HHD should be considered in PD patients in need of a new dialysis modality.
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