Evidence map›Paper›PMID 24584078›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2014

From gut to brain: bioencapsulated therapeutic protein reduces amyloid load upon oral delivery.

Imre Mäger, Thomas C Roberts, Matthew Ja Wood, Samir El Andaloussi

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Gut Microbiota in Neurological Disorders.Archivum immunologiae et therapiae experimentalis · 2019
    Review
  4. Review
  5. Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2016
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Imre MägerDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK; Institute of Technology, University of Tartu, Tartu, Estonia.
Thomas C RobertsDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA.
Matthew Ja WoodDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK.
Samir El AndaloussiDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden. Electronic address: samir.elandaloussi@dpag.ox.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAminopeptidasesAnimalsApolipoproteins EBlood-Brain BarrierBlood-Retinal BarrierChloroplastsCholera ToxinDipeptidyl-Peptidases and Tripeptidyl-PeptidasesFemaleHumansMaleMyelin Basic ProteinNeuronal Ceroid-LipofuscinosesPeptidesPlaque, AmyloidAminopeptidasesApolipoproteins ECholera ToxinDipeptidyl-Peptidases and Tripeptidyl-PeptidasesMyelin Basic ProteinPeptidesSerine ProteasesTripeptidyl-Peptidase 1

Identifiers

PMID24584078
PMCPMC3944335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.