Evidence map›Paper›PMID 24583363›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2014

Familial aggregation of tobacco use behaviors among Amish men.

Katie L Nugent, Amber Million-Mrkva, Joshua Backman, Sarah H Stephens, Robert M Reed, Peter Kochunov, Toni I Pollin, Alan R Shuldiner, Braxton D Mitchell, L Elliot Hong

Open access · bronzeAbstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Depression, stress and regional cerebral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  3. Article
  4. Review
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  6. Article
  7. Article
  8. Article
  9. Nicotine withdrawal.Current topics in behavioral neurosciences · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katie L NugentMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD; knugent@mprc.umaryland.edu.
Amber Million-MrkvaGraduate Program in Epidemiology and Human Genetics, University of Maryland, Baltimore, MD;
Joshua BackmanGraduate Program in Epidemiology and Human Genetics, University of Maryland, Baltimore, MD;
Sarah H StephensDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD;
Robert M ReedDivision of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD;
Peter KochunovMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD;
Toni I PollinDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD;
Alan R ShuldinerDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD;
Braxton D MitchellDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD; Department of Veterans Affairs, Veterans Affairs Medical Center, Baltimore Geriatric Research Education and Clinical Center, Baltimore, MD.
L Elliot HongMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD;
University of Maryland, Baltimore · USGeriatric Research Education and Clinical Center · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
X-LINKED EXTENSION OF THE REVISED HASEMAN-ELSTON ALGORITHM FOR LINKAGE ANALYSISP41RR003655 · NCRR · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI ELSTON, ROBERT C. · 1987 to 2011
$11.5M
Genome-wide Search for CVD Gene-Environment InteractionsU01HL072515 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2002 to 2008
$11.2M
Pharmacogenomics of CVD risk ReductionU01GM074518 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2005 to 2009
$7.3M
SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Multidisciplinary Schizophrenia Research TrainingT32MH067533 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CARPENTER, WILLIAM T., ELMER, GREGORY I · 2004 to 2025
$4.3M
Genetic Influences on Coronary Artery CalcificationR01HL088119 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2007 to 2010
$2.8M
Shared Neural Circuitry in Comorbid Schizophrenia and Nicotine AddictionR01DA027680 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2010 to 2014
$2.4M
Neural Oscillatory Biomarkers for Genetics and Animal Models of SchizophreniaR01MH085646 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2010 to 2013
$2.2M
Joint Determinants of Bone Density and CVD CalcificationR01HL069313 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2001 to 2004
$1.4M
NCRR NIH HHS RR03655NHLBI NIH HHS R01 HL088119NHLBI NIH HHS R01 HL69313NHLBI NIH HHS U01 HL072515NIBIB NIH HHS R01 EB015611NIBIB NIH HHS R01EB015611NIDA NIH HHS R01 DA027680NIDA NIH HHS R01DA027680NIDDK NIH HHS P30 DK072488NIGMS NIH HHS U01 GM074518NIMH NIH HHS R01MH085646NIMH NIH HHS T32 MH067533NIMH NIH HHS T32MH067533
6 · The paper itself

Abstract

introductionTobacco use is a complex behavior. The Old Order Amish community offers unique advantages for the study of tobacco use because of homogenous ancestral background, sociocultural similarity, sex-specific social norms regarding tobacco use, and large family size. Tobacco use in the Old Order Amish community is almost exclusively confined to males.

methodsWe examined characteristics of tobacco use and familial aggregation among 1,216 Amish males from cross-sectional prospectively collected data. Outcomes examined included ever using tobacco regularly, current use, quantity of use, duration of use, and frequency of use.

resultsSixteen percent of Amish men were current tobacco users, with the majority reporting cigar use only. Higher rates of tobacco use were found among sons of fathers who smoked compared with sons of fathers who did not smoke (46% vs. 22%, p < .001) as well as among brothers of index cases who smoked compared with brothers of index cases who did not smoke (61% vs. 29%, p < .001). After controlling for shared household effects and age, heritability accounted for 66% of the variance in ever smoking regularly (p = .045).

conclusionsThe familial patterns of tobacco use observed among Amish men highlight the important role of family in propagating tobacco use and support the usefulness of this population for future genetic studies of nicotine addiction.

Indexed as

AdolescentAdultAgedAged, 80 and overAmishCross-Sectional StudiesFamily CharacteristicsFathersHumansMaleMiddle AgedPennsylvaniaSiblingsSmokingTobacco UseYoung Adult

Identifiers

PMID24583363
PMCPMC4072896
OpenAlexW2129951159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.