Trial reportArchives of physical medicine and rehabilitation2014
Massage therapy restores peripheral vascular function after exertion.
Trial report in Archives of physical medicine and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- Effect ofFrontiers in sports and active living · 2026Trial
- Acute effect of lower-limb peristaltic pulse external pneumatic compression on segmental arterial stiffness in healthy young adults.Physiological reports · 2025Trial
- Peripheral conduit and resistance artery function are improved following a single, 1-h bout of peristaltic pulse external pneumatic compression.European journal of applied physiology · 2015Trial
- Circuit resistance training attenuates acute exertion-induced reductions in arterial function but not inflammation in obese women.Metabolic syndrome and related disorders · 2015Trial
- Technologies to investigate the mechanisms of force-based manipulations: a narrative methods review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Computational modeling of posteroanterior lumbar traction by an automated massage bed: predicting intervertebral disc stresses and deformation.Frontiers in rehabilitation sciences · 2022Article
- Acute and Chronic Periocular Massage for Ocular Blood Flow and Vision: a Randomized Controlled Trial.International journal of therapeutic massage & bodywork · 2021Article
- Sport Performance and Manual Therapies: A Review on the Effects on Mitochondrial, Sarcoplasmatic and CaHealthcare (Basel, Switzerland) · 2021Review
- Massage therapy research review.Complementary therapies in clinical practice · 2016Review
- Panax ginseng and salvia miltiorrhiza supplementation abolishes eccentric exercise-induced vascular stiffening: a double-blind randomized control trial.BMC complementary and alternative medicine · 2016Article
- Short-term high salt intake reduces brachial artery and microvascular function in the absence of changes in blood pressure.Journal of hypertension · 2016Article
- Manual therapy as an effective treatment for fibrosis in a rat model of upper extremity overuse injury.Journal of the neurological sciences · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine if lower extremity exercise-induced muscle injury reduces vascular endothelial function of the upper extremity and if massage therapy (MT) improves peripheral vascular function after exertion-induced muscle injury.
designRandomized, blinded trial with evaluations at 90 minutes, 24 hours, 48 hours, and 72 hours.
settingClinical research center.
participantsSedentary young adults (N=36) were randomly assigned to 1 of 3 groups: (1) exertion-induced muscle injury and MT (n=15; mean age ± SE, 26.6 ± 0.3); (2) exertion-induced muscle injury only (n=10; mean age ± SE, 23.6 ± 0.4), and (3) MT only (n=11; mean age ± SE, 25.5 ± 0.4).
interventionParticipants were assigned to exertion-induced muscle injury only (a single bout of bilateral, eccentric leg press exercise), MT only (30-min lower extremity massage using Swedish technique), or exertion-induced muscle injury and MT.
main outcome measuresBrachial artery flow-mediated dilation (FMD) was determined by ultrasound at each time point. Nitroglycerin (NTG)-induced dilation was also assessed (0.4 mg).
resultsBrachial FMD increased from baseline in the exertion-induced muscle injury and MT group and the MT only group (7.38%±.18% to 9.02%±.28%, P<.05 and 7.77%±.25% to 10.2%±.22%, P<.05, respectively) at 90 minutes and remained elevated until 72 hours. In the exertion-induced muscle injury only group, FMD was reduced from baseline at 24 and 48 hours (7.78%±.14% to 6.75%±.11%, P<.05 and 6.53%±.11%, P<.05, respectively) and returned to baseline after 72 hours. Dilations of NTG were similar over time.
conclusionsOur results suggest that MT attenuates impairment of upper extremity endothelial function resulting from lower extremity exertion-induced muscle injury in sedentary young adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.