ReviewExperimental cell research2014
The tick tock of odontogenesis.
Review in Experimental cell research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Validating Dental Histology for Perinatal Age Estimation Using Human Deciduous Teeth.American journal of biological anthropology · 2026Article
- Influence of circadian rhythm on effects induced by mechanical strain in periodontal ligament cells.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025Article
- Variation in Modern Human Deciduous Molar Enamel Formation Time.American journal of biological anthropology · 2025Article
- Article
- Absence of melatonin during development impairs craniofacial and dental onset in rats.Clinical oral investigations · 2023Article
- Article
- Maternal methylmercury exposure during early-life periods adversely affects mature enamel structure of offspring rats at human exposure levels: a concern for oral health.Frontiers in public health · 2023Article
- Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice.Frontiers in physiology · 2023Article
- Identification of the C-terminal region in Amelogenesis Imperfecta causative protein WDR72 required for Golgi localization.Scientific reports · 2022Article
- Circadian clock-A promising scientific target in oral science.Frontiers in physiology · 2022Review
- Is Pediatric Dentistry a Topic of Interest for Pediatric Journals? A Scoping Review.Children (Basel, Switzerland) · 2021Article
- Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review.Frontiers in cell and developmental biology · 2021Review
- Growth and development of the third permanent molar in Paranthropus robustus from Swartkrans, South Africa.Scientific reports · 2020Article
- Biological clocks and incremental growth line formation in dentine.Journal of anatomy · 2020Article
- Melatonin as an Agent for Direct Pulp-Capping Treatment.International journal of environmental research and public health · 2020Article
- Calcium Sets the Clock in Ameloblasts.Frontiers in physiology · 2020Article
- Chronodentistry: the role & potential of molecular clocks in oral medicine.BMC oral health · 2019Review
- Article
- Heterogeneity and Developmental Connections between Cell Types Inhabiting Teeth.Frontiers in physiology · 2017Review
- Distribution of the amelogenin protein in developing, injured and carious human teeth.Frontiers in physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Although a big deal of dental research is being focused to the understanding of early stages of tooth development, a huge gap exist on our knowledge on how the dental hard tissues are formed and how this process is controlled daily in order to produce very complex and diverse tooth shapes adapted for specific functions. Emerging evidence suggests that clock genes, a family of genes that controls circadian functions within our bodies, regulate also dental mineralized tissues formation. Enamel formation, for example, is subjected to rhythmical molecular signals that occur on short (24h) periods and control the secretion and maturation of the enamel matrix. Accordingly, gene expression and ameloblast functions are also tightly modulated in regular daily intervals. This review summarizes the current knowledge on the circadian controls of dental mineralized tissues development with a special emphasis on amelogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.