ArticleAtencion primaria
The effect of an educational intervention to improve patient antibiotic adherence during dispensing in a community pharmacy.
Article in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Community-based interventions for management of antimicrobial resistance in Europe: a systematic review.European journal of public health · 2026Pooled it
- Does drug dispensing influence patients' medication knowledge and medication adherence? A systematic review and meta-analysis.BMC health services research · 2025Pooled it
- Assessment of global antimicrobial resistance campaigns conducted to improve public awareness and antimicrobial use behaviours: a rapid systematic review.BMC public health · 2024Pooled it
- A systematic literature review and meta-analysis of community pharmacist-led interventions to optimise the use of antibiotics.British journal of clinical pharmacology · 2022Pooled it
- Trial
- Guideline implementation in the Canadian chiropractic setting: a pilot cluster randomized controlled trial and parallel study.Chiropractic & manual therapies · 2019Trial
- Randomized, Controlled, Crossover trial of Prevention of Clindamycin-Induced Gastrointestinal Signs Using a Synbiotic in Healthy Research Cats.Journal of veterinary internal medicine · 2017Trial
- Mediators and Moderators of Improvements in Medication Adherence.Health education & behavior : the official publication of the Society for Public Health Education · 2017Trial
- Stewardship without walls: taming the unregulated antibiotic economy to contain antimicrobial resistance in Ethiopia.Nature communications · 2026Review
- Antimicrobial stewardship interventions involving community pharmacy teams: a scoping review.JAC-antimicrobial resistance · 2025Review
- A Systematic Review of Controlled Trials: Can Patient Adherence to Antibiotics Be Improved Through Pharmaceutical Communication-Based Interventions?Pharmacy (Basel, Switzerland) · 2024Review
- Evaluation of antibiotics returned for safe disposal during and after a community pharmacy antibiotic amnesty campaign.JAC-antimicrobial resistance · 2024Article
- Evaluation of knowledge and practices on antibiotic use: a cross-sectional study on self-reported adherence to short-term antibiotic utilization among patients visiting level-1 hospitals in Lusaka, Zambia.JAC-antimicrobial resistance · 2024Article
- Cross-sectional survey to explore knowledge, attitude, practices and impact of an intervention programme related to antibiotic misuse and self-medication among general population of Pakistan.BMJ public health · 2024Article
- [Audit of Antibiotic Dispensing in Community Pharmacy (Happy Patient Project)].Farmaceuticos comunitarios · 2023Article
- Awareness, practices and perceptions of community pharmacists towards antimicrobial resistance and antimicrobial stewardship in Libya: a cross-sectional study.Journal of pharmaceutical policy and practice · 2023Article
- General Practitioners', Pharmacists' and Parents' Views on Antibiotic Use and Resistance in Malta: An Exploratory Qualitative Study.Antibiotics (Basel, Switzerland) · 2022Article
- Compliance to antibiotic therapy at paediatric out-patient clinic.Journal of family medicine and primary care · 2022Article
- Antibiotics non-adherence and its associated factors among households in southern Ethiopia.SAGE open medicine · 2022Article
- Pharmacist-led intervention in treatment non-adherence and associated direct costs of management among ambulatory patients with type 2 diabetes in southwestern Nigeria.BMC health services research · 2021Article
Corrections and comments
- Commented on byAuthor's reply.2014
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effectiveness of an educational intervention on antibiotic adherence and patient-reported resolution of symptoms.
designA controlled experimental study with systematic assignment to groups.
settingA pharmacy in Murcia. Participants were patients who came to the pharmacy with a prescription for antibiotics. Intervention provided information on treatment characteristics (duration, dose and method of use) and correct compliance. A control group received routine care. Main variables "treatment adherence" and "perceived health" were evaluated one week after dispensation by telephone interview.
resultsA total of 126 patients completed the study, 62 in the Control Group (CG) and 64 in the Intervention Group (IG). There were no differences between the groups in baseline characteristics, including the level of knowledge before the intervention. At the end of the study, treatment adherence in the CG was 48.4% (CI: 36.4-60.6), compared with 67.2% (CI: 55.0-77.4) in the IG. The difference of 18.8% was statistically significant (p=0.033; 95% CI=15.8-34.6). Non-compliance through missing more than one dose was 81.2% in the CG versus 38.1% in the IG, which is a statistically significant difference of 43.1% (p=0.001; 95% CI=16.4-63.1%). No significant differences were found in patient-perceived health. Logistic regression showed as predictor of adherence, the medication knowledge and the coincidence between duration of treatment indicated by physician and duration of treatment written in the prescription.
conclusionsAn educational intervention during antibiotic dispensation improves treatment adherence versus routine care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.