ArticleSchizophrenia research2014
The relationship between suicide and violence in schizophrenia: analysis of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset.
Article in Schizophrenia research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Systematic review of risk factors for violence in psychosis: 10-year update.The British journal of psychiatry : the journal of mental science · 2025Pooled it
- Moderating effects of positive symptoms of psychosis in suicidal ideation among adults diagnosed with schizophrenia.Schizophrenia research · 2016Trial
- Effectiveness of Artificial Intelligence Methods in Personalized Aggression Risk Prediction within Inpatient Psychiatric Treatment Settings-A Systematic Review.Journal of personalized medicine · 2022Review
- Article
- Suicidal ideation in first-episode psychosis: Considerations for depression, positive symptoms, clinical insight, and cognition.Schizophrenia research · 2021Article
- Review
- Neurocognitive Functioning and Suicidal Behavior in Violent Offenders with Schizophrenia Spectrum Disorders.Diagnostics (Basel, Switzerland) · 2020Article
- Performance in Practice: Practice Assessment Tool for the Care of Patients With Schizophrenia.Focus (American Psychiatric Publishing) · 2020Article
- Article
- Suicidality among child and adolescent psychiatric inpatients: time trend study comparing 2000 and 2011.European child & adolescent psychiatry · 2019Article
- Suicidal Ideation in First-Episode Psychosis (FEP): Examination of Symptoms of Depression and Psychosis Among Individuals in an Early Phase of Treatment.Suicide & life-threatening behavior · 2019Article
- Aggressive Behavior, Hostility, and Associated Care Needs in Patients With Psychotic Disorders: A 6-Year Follow-Up Study.Frontiers in psychiatry · 2019Article
- Prediction of Violence, Suicide Behaviors and Suicide Ideation in a Sample of Institutionalized Offenders With Schizophrenia and Other Psychosis.Frontiers in psychology · 2018Article
- Suicidality is a common and serious feature of anti-N-methyl-D-aspartate receptor encephalitis.Journal of neurology · 2017Article
- A longitudinal analysis of the overlap between violence and victimization among adults with mental illnesses.Psychiatry research · 2016Article
- [Interpersonal violence in the context of affective and psychotic disorders].Der Nervenarzt · 2016Review
- Predictors of suicide attempts in 3.322 patients with affective disorders and schizophrenia spectrum disorders.Psychiatry research · 2015Article
- Article
- Symptoms of Depression, Positive Symptoms of Psychosis, and Suicidal Ideation Among Adults Diagnosed With Schizophrenia Within the Clinical Antipsychotic Trials of Intervention Effectiveness.Archives of suicide research : official journal of the International Academy for Suicide ResearchArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSuicide and violence often co-occur in the general population as well as in mentally ill individuals. Few studies, however, have assessed whether these suicidal behaviors are predictive of violence risk in mental illness.
aimsThe aim of this study is to investigate whether suicidal behaviors, including suicidal ideation, threats, and attempts, are significantly associated with increased violence risk in individuals with schizophrenia.
methodData for these analyses were obtained from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial, a randomized controlled trial of antipsychotic medication in 1460 adults with schizophrenia. Univariate Cox regression analyses were used to calculate hazard ratios (HRs) for suicidal ideation, threats, and attempts. Multivariate analyses were conducted to adjust for common confounding factors, including: age, alcohol or drug misuse, major depression, antisocial personality disorder, depression, hostility, positive symptom, and poor impulse control scores. Tests of discrimination, calibration, and reclassification assessed the incremental predictive validity of suicidal behaviors for the prediction of violence risk.
resultsSuicidal threats and attempts were significantly associated with violence in both males and females with schizophrenia with little change following adjustment for common confounders. Only suicidal threats, however, were associated with a significant increase in incremental validity beyond age, diagnosis with a comorbid substance use disorder, and recent violent behavior.
conclusionsSuicidal threats are independently associated with violence risk in both males and females with schizophrenia, and may improve violence risk prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.