Evidence map›Paper›PMID 24581486›Full record

ArticleCell2014

Nuclear pores set the speed limit for mitosis.

Abigail Buchwalter, Martin W Hetzer

Abstract readComment
In one paragraph

Article in Cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Abigail BuchwalterMolecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, 92037 CA, USA.
Martin W HetzerMolecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, 92037 CA, USA. Electronic address: hetzer@salk.edu.

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
Identifying links between the nuclear pore complex and the cell cycleF32GM103084 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BUCHWALTER, ABIGAIL LYNN · 2012 to 2014
$156k
NCI NIH HHS P30 CA014195NIGMS NIH HHS F32 GM103084
6 · The paper itself

Abstract

The spindle assembly checkpoint prevents separation of sister chromatids until each kinetochore is attached to the mitotic spindle. Rodriguez-Bravo et al. report that the nuclear pore complex scaffolds spindle assembly checkpoint signaling in interphase, providing a store of inhibitory signals that limits the speed of the subsequent mitosis.

Indexed as

AnaphaseM Phase Cell Cycle CheckpointsCell Cycle ProteinsHumansMad2 ProteinsNuclear PoreNuclear ProteinsCell Cycle ProteinsMAD1L1 protein, humanMAD2L1 protein, humanMad2 ProteinsNuclear Proteins

Identifiers

PMID24581486
PMCPMC4008093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.